AB178702

Anti-DYNC1LI2/LIC2 antibody [EPR11230(2)]

RabMAb
Recombinant
What is this?

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(5 Publications)

Rabbit Recombinant Monoclonal DYNC1LI2/LIC2 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.

View Alternative Names

DNCLI2, LIC2, DYNC1LI2, Cytoplasmic dynein 1 light intermediate chain 2, LIC53/55, LIC-2

1 Images

Supplier Data

Western blot - Anti-DYNC1LI2/LIC2 antibody [EPR11230(2)] (AB178702)

All lanes:

Western blot - Anti-DYNC1LI2/LIC2 antibody [EPR11230(2)] (ab178702) at 1/1000 dilution

Lane 1:

Human fetal brain lysate at 10 µg

Lane 2:

NCI-H460 lysate at 10 µg

Lane 3:

SK-OV-3 lysate at 10 µg

Predicted band size: 54 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR11230(2)

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

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Product details

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purity

Tissue culture supernatant

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.

See full target information DYNC1LI2

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

The Journal of cell biology 222: PubMed36946995

2023

The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein.

Applications

Unspecified application

Species

Unspecified reactive species

Kirsten E L Garner,Anna Salter,Clinton K Lau,Manickam Gurusaran,Cécile M Villemant,Elizabeth P Granger,Gavin McNee,Philip G Woodman,Owen R Davies,Brian E Burke,Victoria J Allan

Journal of cell science 133: PubMed32467330

2020

Transgelin-2 and phosphoregulation of the LIC2 subunit of dynein govern mitotic spindle orientation.

Applications

Unspecified application

Species

Unspecified reactive species

Amit Sharma,Sunayana Dagar,Sivaram V S Mylavarapu

Nature medicine 24:802-813 PubMed29785027

2018

Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Norifumi Shioda,Yasushi Yabuki,Kouya Yamaguchi,Misaki Onozato,Yue Li,Kenji Kurosawa,Hideyuki Tanabe,Nobuhiko Okamoto,Takumi Era,Hiroshi Sugiyama,Takahito Wada,Kohji Fukunaga

Scientific reports 6:22 PubMed28003657

2016

The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation.

Applications

Unspecified application

Species

Unspecified reactive species

Sagar Mahale,Megha Kumar,Amit Sharma,Aswini Babu,Shashi Ranjan,Chetana Sachidanandan,Sivaram V S Mylavarapu

PloS one 11:e0159646 PubMed27441562

2016

Dynein Light Intermediate Chain 2 Facilitates the Metaphase to Anaphase Transition by Inactivating the Spindle Assembly Checkpoint.

Applications

Species

Human

Sagar P Mahale,Amit Sharma,Sivaram V S Mylavarapu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-DYNC1LI2/LIC2 antibody [EPR11230(2)]

Western blot - Anti-DYNC1LI2/LIC2 antibody [EPR11230(2)] (AB178702)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (5)

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