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AB225946

Anti-DYNC2H1 antibody

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(2 Publications)

Rabbit Polyclonal DYNC2H1 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Recombinant fragment - Human, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human DYNC2H1 aa 1900-2100.

View Alternative Names

DHC1B, DHC2, DNCH2, DYH1B, KIAA1997, DYNC2H1, Cytoplasmic dynein 2 heavy chain 1, Cytoplasmic dynein 2 heavy chain, Dynein cytoplasmic heavy chain 2, Dynein heavy chain 11, Dynein heavy chain isotype 1B, hDHC11

4 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DYNC2H1 antibody (AB225946)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DYNC2H1 antibody (AB225946)

Paraffin-embedded human testis tissue stained for DYNC2H1 with ab225946 at 1/100 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-DYNC2H1 antibody (AB225946)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-DYNC2H1 antibody (AB225946)

HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for DYNC2H1 (green) using ab225946 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® congugated Goat Anti-Rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DYNC2H1 antibody (AB225946)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DYNC2H1 antibody (AB225946)

Paraffin-embedded human small intestine tissue stained for DYNC2H1 with ab225946 at 1/100 dilution in immunohistochemical analysis.

Western blot - Anti-DYNC2H1 antibody (AB225946)
  • WB

Supplier Data

Western blot - Anti-DYNC2H1 antibody (AB225946)

Predicted MW of recombinant protein : 45 kDa.

All lanes:

Western blot - Anti-DYNC2H1 antibody (ab225946) at 1/500 dilution

Lane 1:

Recombinant Human DYNC2H1 protein with N-terminal GST tag, 80 ng

Lane 2:

Recombinant Human DYNC2H1 protein with N-terminal GST tag, 40 ng

Lane 3:

Recombinant Human DYNC2H1 protein with N-terminal GST tag, 20 ng

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/50000 dilution

Predicted band size: 493 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human DYNC2H1 aa 1900-2100. The exact immunogen used to generate this antibody is proprietary information.

Q8NCM8

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Recombinant fragment - Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis. May play a role in transport between endoplasmic reticulum and Golgi or organization of the Golgi in cells (By similarity).
See full target information DYNC2H1
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

General physiology and biophysics 44:349-361 PubMed40923655

2025

HuR enhances the stability of FGF19 mRNA to suppress Kupffer cell activation and mitigate inflammation and fibrosis in non-alcoholic fatty liver disease.

Applications

Unspecified application

Species

Unspecified reactive species

XiaoQing Mo,SiJun Zhou,XiaoGe Zhou,Chun Huang

The EMBO journal 43:1257-1272 PubMed38454149

2024

Structure and tethering mechanism of dynein-2 intermediate chains in intraflagellar transport.

Applications

Unspecified application

Species

Unspecified reactive species

Aakash G Mukhopadhyay,Katerina Toropova,Lydia Daly,Jennifer N Wells,Laura Vuolo,Miroslav Mladenov,Marian Seda,Dagan Jenkins,David J Stephens,Anthony J Roberts
View all publications
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Product promise

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