JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB68748

Anti-EFCAB6 antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Mouse Polyclonal EFCAB6 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human EFCAB6.

View Alternative Names

DJBP, KIAA1672, EFCAB6, EF-hand calcium-binding domain-containing protein 6, CAP-binding protein complex-interacting protein 1, DJ-1-binding protein

1 Images
Western blot - Anti-EFCAB6 antibody (AB68748)
  • WB

Unknown

Western blot - Anti-EFCAB6 antibody (AB68748)

All lanes:

Western blot - Anti-EFCAB6 antibody (ab68748) at 1/500 dilution

Lane 1:

EFCAB6 transfected 293T cell lysate at 25 µg

Lane 2:

non transfected 293T cell lysate at 25 µg

Secondary

All lanes:

Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/5000 dilution

Predicted band size: 173 kDa

Observed band size: 156 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human EFCAB6.

Q5THR3

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p>Predicted molecular weight for isoform 2.</p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

EFCAB6 also known as DJBP (DnaJ homolog subfamily B member 14 binding protein) is a calcium-binding protein with a molecular mass of approximately 89 kDa. This protein features multiple EF-hand motifs that facilitate its role in binding calcium ions affecting its structural conformation and function. EFCAB6 expresses in various tissues with a notable presence in the heart brain and testis suggesting a specialized role in these locations. Its calcium-binding ability suggests involvement in processes regulated by calcium signaling.
Biological function summary

EFCAB6 plays an important role in maintaining cellular calcium homeostasis and signaling pathways. It acts as a modulator within signal transduction pathways that rely on calcium ions and sometimes it participates as part of larger protein complexes. The interaction between EF-hands and calcium allows EFCAB6 to regulate activities in the cell that rely on transient calcium variations.

Pathways

Researchers recognize EFCAB6 for its involvement in calcium signaling and the regulation of cell cycle-related pathways. It exhibits interaction with proteins such as KITLG (Kit Ligand) and CALM1 (Calmodulin 1) which play key roles in signaling pathways. Through these interactions EFCAB6 helps regulate processes important for cell division and proliferation.

EFCAB6 links with certain heart disorders and neurological conditions. Alterations in its calcium-binding capacity may contribute to irregular heart rhythms and contribute to neurodegenerative diseases. EFCAB6's interaction with proteins like CACNA1C (calcium voltage-gated channel subunit alpha1 C) and PRKCA (protein kinase C alpha) connects it to these conditions as disruptions in these interactions may lead to pathophysiological consequences.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex (PubMed : 12612053). Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity).
See full target information EFCAB6
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Microbiology spectrum 13:e0162624 PubMed39932324

2025

C-reactive protein-induced injury in -infected lung epithelial cells is mediated by the P38 MAPK/mitochondrial apoptosis pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Lianjia Li,Yang Zhang,Lin Zhao,Yalin Shi
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB68719

Anti-HP1BP3 antibody

Western blot - Anti-HP1BP3 antibody (AB68719)

  • 0
  • 0
Primary Antibodies

AB68713

Anti-GORASP2/GRASP55 antibody

Western blot - Anti-GORASP2/GRASP55 antibody (AB68713)

  • 4
  • 1
Primary Antibodies

AB205064

Anti-GBA2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GBA2 antibody (AB205064)

  • 1
  • 2
Primary Antibodies

AB66978

Anti-HSP1 / Protamine P1 antibody

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com