JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB118599

Anti-EFHD1 antibody

0

(1 Review)

|

(1 Publication)

Rabbit Polyclonal EFHD1 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human EFHD1 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

SWS2, PP3051, EFHD1, EF-hand domain-containing protein D1, EF-hand domain-containing protein 1, Swiprosin-2

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EFHD1 antibody (AB118599)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EFHD1 antibody (AB118599)

ab118599, at 5 µg/ml, staining EFHD1 in formalin fixed, paraffin embedded Human lung tissue by Immunohistochemistry.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EFHD1 antibody (AB118599)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EFHD1 antibody (AB118599)

ab118599, at 5 µg/ml, staining EFHD1 in formalin fixed, paraffin embedded Human adrenal tissue by Immunohistochemistry.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human EFHD1 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q9BUP0

style
left-column

Complementary Products

Primary Antibodies

AB137060

Anti-Amino-terminal enhancer of split/AES antibody [EPR8385]

RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-Amino-terminal enhancer of split/AES antibody [EPR8385] (AB137060)

  • 0
  • 0
Primary Antibodies

AB249162

Anti-PPP3CC antibody [EPR10601] - BSA and Azide free

RabMAb|Recombinant

Western blot - Anti-PPP3CC antibody [EPR10601] - BSA and Azide free (AB249162)

  • 0
  • 0
Primary Antibodies

AB47252

Anti-SPANX antibody

Western blot - Anti-SPANX antibody (AB47252)

  • 0
  • 0
Primary Antibodies

AB118458

Anti-SEMAC antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SEMAC antibody (AB118458)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5 µg/mL", "IHCP-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

EFHD1 also known as EF-hand domain family member D1 is a protein encoded by the EFHD1 gene. This protein weighs approximately 25 kDa and is involved in calcium-binding due to its EF-hand domains. EFHD1 is expressed in various tissues including the skeletal muscles and brain. Its expression in these tissues suggests potential roles in muscle function and neurological processes.
Biological function summary

EFHD1 participates in the regulation of cellular processes through calcium signaling. It acts as a modulator adjusting cellular responses to alterations in calcium levels. While not a component of a larger protein complex EFHD1 interacts with other calcium-binding proteins which may enhance its regulatory functions in cellular activities.

Pathways

Calcium-binding properties of EFHD1 enable it to interact with signal transduction and apoptosis pathways. Its involvement in calcium-mediated signal transduction helps in the transmission of messages within cells which affects cell function and survival. EFHD1 may interact with proteins such as calmodulin indicating a role in the modulation of calcium-dependent signaling events.

EFHD1 has connections to neurodegenerative diseases such as Alzheimer's disease. Its role in calcium regulation links it to the dysfunction observed in these disorders where calcium imbalance leads to cellular damage. EFHD1 also associates with proteins like tau which are implicated in Alzheimer's pathology hinting at potential pathways for disease modulation or therapeutic targeting.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production (PubMed : 26975899). May play a role in neuronal differentiation (By similarity).
See full target information EFHD1
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Molecular reproduction and development 92:e70049 PubMed40838423

2025

Three-Dimensional Magnetic Bioprinting Spheroids as an In Vitro Model to Study the Oviductal Physiology.

Applications

Unspecified application

Species

Unspecified reactive species

Patricia Kubo Fontes,Ana Beatriz Florencio da Silva,Ana Beatriz Dos Reis Bartoli,Thays Antunes,Arnaldo Rodrigues Dos Santos Júnior,Marcella Pecora Milazzotto
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com