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Rabbit Recombinant Monoclonal Embigin homolog antibody. Carrier free. Suitable for IP, Flow Cyt, WB and reacts with Human samples.

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Images

Immunoprecipitation - Anti-Embigin homolog antibody [EPR11417] - BSA and Azide free (AB250110), expandable thumbnail
  • Western blot - Anti-Embigin homolog antibody [EPR11417] - BSA and Azide free (AB250110), expandable thumbnail
  • Flow Cytometry - Anti-Embigin homolog antibody [EPR11417] - BSA and Azide free (AB250110), expandable thumbnail

Key facts

Isotype

IgG

Host species

Rabbit

Storage buffer

pH: 7.2 - 7.4
Constituents: PBS

Form

Liquid

Clonality

Monoclonal

Immunogen

  • The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
IPFlow CytWBIHC-PICC/IF
Human
Tested
Tested
Tested
Not recommended
Not recommended

Tested
Tested

Species

Human

Dilution info

-

Notes

-

Tested
Tested

Species

Human

Dilution info

-

Notes

-

Tested
Tested

Species

Human

Dilution info

-

Notes

-

Not recommended
Not recommended

Species

Human

Dilution info

-

Notes

-

Not recommended
Not recommended

Species

Human

Dilution info

-

Notes

-

Target data

Function

Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1, SLC16A6 and SLC16A7 to the cell membrane (By similarity).

Alternative names

Recommended products

Rabbit Recombinant Monoclonal Embigin homolog antibody. Carrier free. Suitable for IP, Flow Cyt, WB and reacts with Human samples.

Key facts

Isotype

IgG

Form

Liquid

Clonality

Monoclonal

Immunogen
  • The exact immunogen used to generate this antibody is proprietary information.
Carrier free

Yes

Clone number

EPR11417

Purification technique

Affinity purification

Concentration
Loading...

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Storage information

Do Not Freeze

Notes

ab250110 is the carrier-free version of Anti-Embigin homolog antibody [EPR11417] ab179801.

Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. The carrier-free buffer and high concentration allow for increased conjugation efficiency.

This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

The Embigin homolog protein often referred to simply as Embigin plays an important mechanical role within the cell. It is a transmembrane protein with a molecular mass of approximately 41 kDa. Researchers have observed Embigin expressed mostly in the tissues of the developing central nervous system and muscle tissues. It is also detected in adult tissues but in distinct expression patterns including the heart and the testis.

Biological function summary

Embigin is involved in the regulation of cell adhesion and proliferation. It is not generally part of a larger protein complex but acts as a facilitator of cellular interactions particularly during tissue morphogenesis and development. Embigin's role in promoting cell aggregation involves interaction with other cell surface proteins influencing cellular dynamics during development.

Pathways

Embigin plays a role in the integrin signaling pathway. It interacts with integrins which are transmembrane receptors involved in cell adhesion sending signals that regulate the cytoskeleton and the cell cycle. Another pathway related to Embigin's function is the PI3K/Akt signaling pathway. Through this pathway Embigin indirectly influences cellular survival and growth processes closely interacting with signaling proteins like PI3K.

Associated diseases and disorders

Researchers have linked Embigin to cancer and neurodegenerative conditions. Changes in Embigin expression have been connected to various cancers as the protein influences cell adhesion and migration which are critical in tumor progression. In neurodegenerative diseases altered expression of Embigin affects cellular interactions in neural tissues relating to proteins like the neural cell adhesion molecule which further impacts neural health and connectivity.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com