Rabbit Polyclonal ENPP5 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human ENPP5.
View Alternative Names
UNQ550/PRO1107, ENPP5, Ectonucleotide pyrophosphatase/phosphodiesterase family member 5, E-NPP 5, NPP-5
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ENPP5 antibody (AB197391)
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue labeling ENPP5 with ab197391 at a 1/40 dilution.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ENPP5 antibody (AB197391)
Immunohistochemical analysis of paraffin-embedded human tonsil cancer tissue labeling ENPP5 with ab197391 at a 1/40 dilution.
Reactivity data
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Supplementary information
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Biological function summary
Researchers propose that ENPP5 contributes to nucleotide metabolism and signaling processes. Although ENPP5 is not directly part of a larger protein complex it functions alongside similar enzymes sharing common substrates and physiological roles. By maintaining balance in the extracellular nucleotide levels ENPP5 can influence processes such as cellular signaling potentially affecting cell growth and differentiation in its primary tissues.
Pathways
ENPP5 activity relates to purine metabolism and the signal transduction pathways that involve nucleotides. One primary pathway where it plays a role is the nucleotide catabolic process interacting indirectly with proteins such as ENPP1 and ENPP2 that manage pyrophosphate and phospholipid metabolism. ENPP5 by breaking down nucleotides influences signal transduction pathways like the P2Y receptor-mediated pathways which are important for various physiological functions.
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Target data
Publications (1)
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Life metabolism 1:242-257 PubMed39872077
2022
Applications
Unspecified application
Species
Unspecified reactive species
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