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AB110711

Anti-ENTPD2 antibody [EPR3885]

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(1 Publication)

Rabbit Recombinant Monoclonal ENTPD2 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

CD39L1, ENTPD2, Ectonucleoside triphosphate diphosphohydrolase 2, E-NTPDase 2, NTPDase 2, CD39 antigen-like 1, Ecto-ATP diphosphohydrolase 2, Ecto-ATPDase 2, Ecto-ATPase 2

1 Images
Western blot - Anti-ENTPD2 antibody [EPR3885] (AB110711)
  • WB

Unknown

Western blot - Anti-ENTPD2 antibody [EPR3885] (AB110711)

All lanes:

Western blot - Anti-ENTPD2 antibody [EPR3885] (ab110711) at 1/1000 dilution

Lane 1:

Human placenta cell lysate at 10 µg

Lane 2:

JAR cell lysate at 10 µg

Lane 3:

Human fetal kidney cell lysate at 10 µg

Lane 4:

U-87MG cell lysate at 10 µg

Predicted band size: 54 kDa

false

  • Carrier free

    Anti-ENTPD2 antibody [EPR3885] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR3885

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" }, "Mouse": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Conditional Ambient
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Stable for 12 months at -20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ENTPD2 also known as ectonucleoside triphosphate diphosphohydrolase 2 or CD39L1 functions as an enzyme that hydrolyzes nucleoside triphosphates and diphosphates into their respective monophosphates while releasing inorganic phosphate. It has a molecular mass of approximately 61 kDa. This protein is expressed in many tissues with a notable presence in the human liver placenta and pancreas. Its expression on endothelial and epithelial cells suggests active involvement in vascular and surface barrier systems.
Biological function summary

ENTPD2 participates in the regulation of extracellular nucleotide levels which influences various physiological processes. It works as part of the nucleoside triphosphate diphosphohydrolase family that controls purinergic signaling by degrading high-energy nucleotides. This regulation affects cellular activities such as proliferation and apoptosis. Its role is critical in modulating the availability of nucleotides for homeostatic and stress responses in the body.

Pathways

ENTPD2 is involved in purinergic signaling and ATP metabolism pathways. These pathways are significant in maintaining cellular energy balance and facilitating communication between cells through signaling molecules like ATP and ADP. ENTPD2 has a functional interplay with other proteins like ENTPD1 and adenosine deaminase during these processes ensuring tight regulation of extracellular nucleotides and their products.

ENTPD2 shows associations with cancer particularly hepatocellular carcinoma and inflammatory diseases. It is an important player in cancer due to its ability to modulate the tumor microenvironment through purinergic signaling influencing tumor growth and metastasis. Inflammatory responses also connect to ENTPD2 activity where altered expression can contribute to chronic inflammation conditions. The protein's interaction with CD39 another member of the ectonucleotidase family highlights its important role in these pathological contexts.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP.
See full target information ENTPD2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

PloS one 7:e40829 PubMed22792409

2012

Increased CD39 nucleotidase activity on microparticles from patients with idiopathic pulmonary arterial hypertension.

Applications

BL

Species

Human

Scott H Visovatti,Matthew C Hyman,Diane Bouis,Richard Neubig,Vallerie V McLaughlin,David J Pinsky
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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