Anti-EpCAM antibody
4
(2 Reviews)
|
(2 Publications)
Rabbit Polyclonal EPCAM antibody. Suitable for IHC-P, WB and reacts with Rat, Rabbit, Mouse samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Mouse Epcam aa 50-150 conjugated to Keyhole Limpet Haemocyanin.
View Alternative Names
CD326, Tacstd1, Epcam, Epithelial cell adhesion molecule, Ep-CAM, Epithelial glycoprotein 314, Protein 289A, Tumor-associated calcium signal transducer 1, EGP314, mEGP314
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EpCAM antibody (AB216832)
Immunohistochemical analysis of formalin-fixed paraffin-embedded rat brain tissue, labeling EpCAM using ab216832 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
- WB
Supplier Data
Western blot - Anti-EpCAM antibody (AB216832)
12% gel.
All lanes:
Western blot - Anti-EpCAM antibody (ab216832) at 1/200 dilution
Lane 1:
mouse brain lysate
Lane 2:
mouse liver lysate
Secondary
All lanes:
Goat Anti-Rabbit IgG Antibody (H+L), HRP Conjugated at 1/3000 dilution
Predicted band size: 35 kDa
Observed band size: 32 kDa
true
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EpCAM antibody (AB216832)
Immunohistochemical analysis of formalin-fixed paraffin-embedded rabbit bladder tissue, labeling EpCAM using ab216832 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EpCAM antibody (AB216832)
Immunohistochemical analysis of formalin-fixed paraffin-embedded rabbit bladder tissue, labeling EpCAM using ab216832 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
Reactivity data
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Supplementary information
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Biological function summary
EpCAM facilitates signaling pathways that impact cellular processes like proliferation and differentiation. It is not a part of a larger protein complex but interacts directly with other cellular machinery to transmit intracellular signals. EpCAM influences stem cell behavior and is important in tissue homeostasis assisting in both normal regenerative processes and wound healing.
Pathways
EpCAM participates in regulatory mechanisms involving the Wnt/β-catenin signaling pathway which affects gene expression and cell fate decisions. Through its action EpCAM modulates components like E-cadherin which is important for cell adhesion and the maintenance of the epithelial layer. It indirectly influences pathways relating to MYC a transcription factor that regulates cell cycle progression and apoptosis.
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Target data
Publications (2)
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Stem cell research & therapy 14:45 PubMed36941658
2023
Applications
Unspecified application
Species
Unspecified reactive species
Cellular physiology and biochemistry : internation 51:1600-1615 PubMed30497067
2018
Applications
Unspecified application
Species
Unspecified reactive species
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