- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Erythrocytes antibody (AB197770)
Formalin-fixed, paraffin-embedded Human placenta tisue labeling Erythrocytes using ab197770 at 2.5 μg/ml.
Reactivity data
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Erythrocytes facilitate respiratory gas exchange throughout the body. They are not part of a complex but rely heavily on hemoglobin's function. Each hemoglobin molecule contains four heme groups each capable of binding an oxygen molecule. Erythrocytes lack nuclei which maximizes space for hemoglobin and optimizes their gas-carrying capacity. The absence of other cellular organelles reduces energy consumption making erythrocytes highly efficient in gas transport.
Pathways
Erythrocytes participate in the glycolytic pathway to generate ATP due to the absence of mitochondria. This helps to power cellular processes and maintain ion gradients. The pentose phosphate pathway is also relevant providing reduction power in the form of NADPH. This is essential for maintaining the integrity of the cell membrane and protecting erythrocytes from oxidative damage. Related proteins such as glucose-6-phosphate dehydrogenase support these pathways by facilitating critical reactions.
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
Target data
Publications (3)
Recent publications for all applications. Explore the full list and refine your search
Frontiers in immunology 12:777402 PubMed34858435
2021
Applications
Unspecified application
Species
Unspecified reactive species
JCI insight 4: PubMed31661468
2019
Applications
Unspecified application
Species
Unspecified reactive species
International journal of molecular medicine 41:2704-2714 PubMed29436579
2018
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com