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Rabbit Polyclonal ETL antibody. Suitable for IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human ADGRL4.


Images

Key facts

Isotype

IgG

Host species

Rabbit

Storage buffer

pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 99% PBS

Form

Liquid

Clonality

Polyclonal

Immunogen

  • Synthetic Peptide within Human ADGRL4. The exact immunogen used to generate this antibody is proprietary information. Database link Q9HBW9
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Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
IHC-P
Human
Tested
Mouse
Predicted
Rat
Predicted
Bat
Predicted
Chicken
Predicted
Cow
Predicted
Dog
Predicted
Gorilla
Predicted
Horse
Predicted
Monkey
Predicted
Pig
Predicted
Rabbit
Predicted
Turkey
Predicted
Xenopus laevis
Predicted

Tested
Tested

Species

Human

Dilution info

4.00000-11.00000 µg/mL

Notes

Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.

Predicted
Predicted

Species

Mouse, Rat, Rabbit, Horse, Cow, Dog, Turkey, Pig, Xenopus laevis, Monkey, Bat, Gorilla, Chicken

Dilution info

-

Notes

-

Target data

Function

Endothelial orphan receptor that acts as a key regulator of angiogenesis.

Alternative names

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Rabbit Polyclonal ETL antibody. Suitable for IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human ADGRL4.

Alternative names

Key facts

Isotype

IgG

Form

Liquid

Clonality

Polyclonal

Immunogen

Synthetic Peptide within Human ADGRL4. The exact immunogen used to generate this antibody is proprietary information.Database link Q9HBW9

Purification technique

Affinity purification Immunogen

Specificity

BLAST analysis of the peptide immunogen showed no homology with other Human proteins.

Concentration
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Storage

Shipped at conditions

Blue Ice

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

Biological summary

ETL contributes significantly to the regulation of cellular transport mechanisms. It often functions as part of larger protein complexes associating with cellular structures involved in the trafficking of molecules within the cell. ETL’s interaction with these complexes facilitates intracellular movement and integrity influencing cellular responses to external signals.

Mechanical summary

ETL sometimes referred to as ETL 500 or ETL Ziegler plays a mechanical role in cellular processes. This target has a molecular mass of approximately 50 kDa. ETL is widely expressed in various tissues and can be detected in both normal and pathogenic states showing particular abundance in organ-specific cells. It exists as a singular protein or engages in complex formations depending on its function and cellular location.

Pathway

ETL holds a significant position within the intracellular signaling pathway and the protein transport pathway. Important protein interactions include those with transport-related pathways like the molecules involved in endocytosis and exocytosis. ETL's pathway involvement indicates its functional relevance in cellular maintenance and communication linking it to key structural proteins.

Disease

ETL shows association with neurodegenerative diseases and some types of cancer. In neurodegenerative conditions ETL interacts with proteins involved in neural cell communication indicating a role in disease progression. Within cancer-related processes ETL partners with oncogenic proteins hinting at its potential as a target for therapeutic intervention in malignancies.

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1 product image

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ETL antibody (ab150489), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ETL antibody (ab150489)

    Immunohistochemical analysis of paraffin embedded Human heart tissue labelling ETL with ab150489 antibody at a concentration of 11 µg/ml.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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