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AB168290

Anti-ETNK2 antibody

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(1 Publication)

Mouse Polyclonal ETNK2 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human ETNK2.

View Alternative Names

EKI2, HMFT1716, ETNK2, Ethanolamine kinase 2, EKI 2, Ethanolamine kinase-like protein

1 Images
Western blot - Anti-ETNK2 antibody (AB168290)
  • WB

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Western blot - Anti-ETNK2 antibody (AB168290)

All lanes:

Western blot - Anti-ETNK2 antibody (ab168290) at 1 µg/mL

Lane 1:

ETNK2 transfected 293T cell lysate at 15 µL

Lane 2:

Non-transfected 293T cell lysate at 15 µL

Predicted band size: 44 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human ETNK2.

Q9NVF9

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ETNK2 also known as ethanolamine kinase 2 is an enzyme involved in the phospholipid biosynthesis pathway. This protein weighs approximately 44 kDa and is expressed in various tissues including the liver and brain. It plays an important role in the conversion of ethanolamine to phosphoethanolamine which is an important step in the production of phosphatidylethanolamine an important component of cell membranes.
Biological function summary

Ethanolamine kinase 2 facilitates the synthesis of phosphatidylethanolamine by functioning as part of the Kennedy pathway an essential process for membrane biogenesis and maintenance. Although not part of a known structural complex it functions closely with other metabolic enzymes to ensure efficient production of phospholipids. This enzyme contributes to maintaining proper cellular structures and signaling pathways by affecting membrane composition and dynamics.

Pathways

Ethanolamine kinase 2 significantly contributes to the CDP-ethanolamine pathway one of the two main routes for phosphatidylethanolamine biosynthesis. It works together with other enzymes like CTP:phosphoethanolamine cytidylyltransferase to regulate the availability of phosphatidylethanolamine. This pathway is important for maintaining cellular lipid homeostasis and supporting membrane-based cellular processes.

Ethanolamine kinase 2 has a connection to neurological conditions because of its significant role in phospholipid metabolism. Abnormalities in its function or expression can potentially lead to disorders such as metabolic syndrome and nonalcoholic fatty liver disease. In these contexts its activity links with other proteins involved in lipid metabolism such as phosphatidylethanolamine N-methyltransferase suggesting potential therapeutic targets within these pathways.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity).
See full target information ETNK2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 6:8100 PubMed26311497

2015

PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus.

Applications

Unspecified application

Species

Unspecified reactive species

Daqian Xu,Zheng Wang,Yuxue Zhang,Wei Jiang,Yi Pan,Bao-Liang Song,Yan Chen
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