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AB97797

Anti-FAM122B antibody

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(1 Publication)

Rabbit Polyclonal FAM122B antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human PABIR2 aa 1-200.

View Alternative Names

FAM122B, PABIR2, PABIR family member 2

1 Images
Western blot - Anti-FAM122B antibody (AB97797)
  • WB

Unknown

Western blot - Anti-FAM122B antibody (AB97797)

12% SDS PAGE

All lanes:

Western blot - Anti-FAM122B antibody (ab97797) at 1/1000 dilution

All lanes:

HCT116 whole cell lysate at 30 µg

Predicted band size: 27 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human PABIR2 aa 1-200. The exact immunogen used to generate this antibody is proprietary information.

Q7Z309

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FAM122B also known as Protein Family with Sequence Similarity 122B is involved in several cellular processes. Its mass is approximately 15 kDa. The expression of FAM122B occurs in various tissues including the brain lungs and liver indicating its importance in different physiological contexts. Mechanically FAM122B interacts with proteins at a molecular level though specific mechanisms need detailed research for full understanding.
Biological function summary

The functions of FAM122B extend across several cellular activities. It participates in protein complexes that may regulate cell growth and signaling. The exact biological roles are still under investigation but evidence points to its involvement in critical cellular signaling pathways. As a member of larger multiprotein complexes FAM122B contributes to intracellular communication and regulatory processes.

Pathways

The participation of FAM122B in signaling and regulatory networks is apparent. It associates with pathways like the PI3K-Akt signaling pathway which is essential for cell proliferation and survival. In these pathways FAM122B interacts with proteins such as Akt and mTOR playing a role in modulating downstream effects. Through its interactions FAM122B impacts cellular responses to environmental and molecular signals.

FAM122B has connections to various pathological conditions. Abnormal expression or functioning of FAM122B is linked to certain types of cancer and neurodegenerative diseases. In cancer it may interact with proteins like p53 influencing tumor suppression mechanisms. While research continues understanding FAM122B's role in these diseases can present new therapeutic opportunities for diagnosis and treatment.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information PABIR2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 11:190 PubMed31929512

2020

Sestrins are evolutionarily conserved mediators of exercise benefits.

Applications

Unspecified application

Species

Unspecified reactive species

Myungjin Kim,Alyson Sujkowski,Sim Namkoong,Bondong Gu,Tyler Cobb,Boyoung Kim,Allison H Kowalsky,Chun-Seok Cho,Ian Semple,Seung-Hyun Ro,Carol Davis,Susan V Brooks,Michael Karin,Robert J Wessells,Jun Hee Lee
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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