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AB184160

Anti-FAM160A2 antibody [EPR13604]

5

(1 Review)

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(2 Publications)

Rabbit Recombinant Monoclonal FAM160A2 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications.

View Alternative Names

C11orf56, FAM160A2, KIAA1759, FHIP1B, FHF complex subunit HOOK-interacting protein 1B, FTS- and Hook-interacting protein, FHIP

2 Images
Western blot - Anti-FAM160A2 antibody [EPR13604] (AB184160)
  • WB

Supplier Data

Western blot - Anti-FAM160A2 antibody [EPR13604] (AB184160)

All lanes:

Western blot - Anti-FAM160A2 antibody [EPR13604] (ab184160) at 1/1000 dilution

Lane 1:

HeLa lysate at 10 µg

Lane 2:

Human fetal brain lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 106 kDa

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Western blot - Anti-FAM160A2 antibody [EPR13604] (AB184160)
  • WB

CiteAb

Western blot - Anti-FAM160A2 antibody [EPR13604] (AB184160)

FAM160A2 western blot using anti-FAM160A2 antibody [EPR13604] ab184160. Publication image and figure legend from Redwine, W. B., DeSantis, M. E., et al., 2017, Elife, PubMed 28718761.

ab184160 was used in this publication in western blot. This may not be the same as the application(s) guaranteed by Abcam. For a full list of applications guaranteed by Abcam for ab184160 please see the product overview.

KIF1C is a novel HOOK3-interacting protein.sfGFP-3×FLAG and full length (FL) HOOK3, HOOK3 (1–552), and HOOK3 (553–718) all tagged with sfGFP and 3×FLAG were immunoprecipitated with α-FLAG antibodies from transiently transfected HEK-293T cells. Western blots with α-HC, α-FAM160A2, α-KIF1C, and α-FLAG antibodies were used to determine which proteins co-immunoprecipitated with each HOOK3 construct.DOI : http : //dx.doi.org/10.7554/eLife.28257.015

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  • Carrier free

    Anti-FAM160A2 antibody [EPR13604] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR13604

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FAM160A2 also known as Family with Sequence Similarity 160 Member A2 is a protein involved in cellular processes. It has a mass of approximately 81 kDa. Researchers have found FAM160A2 expressed in various human tissues with notable presence in the brain and liver. The protein features a conserved region typical for this family suggesting a specific cellular role possibly related to protein-protein interactions.
Biological function summary

FAM160A2 contributes to cellular organization and homeostasis. It assists in regulating intracellular signaling pathways possibly working as part of larger protein complexes. This involvement in cellular signaling pathways implies that FAM160A2 plays a part in maintaining the normal function of cells. It can impact processes such as signal transduction and cellular communication though its precise biological functions remain under study.

Pathways

Research indicates that FAM160A2 participates in signaling cascades such as the MAPK pathway and the apoptosis pathway. Through the MAPK pathway it may act alongside proteins like ERK1/2 to regulate cellular responses to stimuli including stress and growth signals. In the apoptosis pathway FAM160A2's role possibly associates with proteins like Bcl-2 influencing cell death decisions which are critical for tissue development and immune response.

Scientific findings suggest FAM160A2's involvement in neurodegenerative diseases and some liver conditions. In neurodegeneration its interaction with proteins such as Tau could contribute to molecular mechanisms leading to neuronal dysfunction. In liver-related disorders FAM160A2 might connect with proteins involved in metabolic regulation indicating its role in conditions characterized by metabolic imbalance. Understanding these connections could guide future research and therapeutic strategies.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed : 32073997).
See full target information FHIP1B
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Molecular biology of the cell 31:963-979 PubMed32073997

2020

The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A.

Applications

Unspecified application

Species

Unspecified reactive species

Rafael Mattera,Chad D Williamson,Xuefeng Ren,Juan S Bonifacino

eLife 6: PubMed28718761

2017

The human cytoplasmic dynein interactome reveals novel activators of motility.

Applications

Unspecified application

Species

Unspecified reactive species

William B Redwine,Morgan E DeSantis,Ian Hollyer,Zaw Min Htet,Phuoc Tien Tran,Selene K Swanson,Laurence Florens,Michael P Washburn,Samara L Reck-Peterson
View all publications
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Product promise

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