JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB250719

Anti-FAM160A2 antibody [EPR13604] - BSA and Azide free

Be the first to review this product! Submit a review

|

(2 Publications)

Rabbit Recombinant Monoclonal FAM160A2 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 2 publications.

View Alternative Names

C11orf56, FAM160A2, KIAA1759, FHIP1B, FHF complex subunit HOOK-interacting protein 1B, FTS- and Hook-interacting protein, FHIP

1 Images
Western blot - Anti-FAM160A2 antibody [EPR13604] - BSA and Azide free (AB250719)
  • WB

Supplier Data

Western blot - Anti-FAM160A2 antibody [EPR13604] - BSA and Azide free (AB250719)

This data was developed using ab184160, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-FAM160A2 antibody [EPR13604] (<a href='/en-us/products/primary-antibodies/fam160a2-antibody-epr13604-ab184160'>ab184160</a>) at 1/1000 dilution

Lane 1:

HeLa lysate at 10 µg

Lane 2:

Human fetal brain lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 106 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR13604

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
style
left-column

Product details

ab250719 is the carrier-free version of ab184160.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FAM160A2 also known as Family with Sequence Similarity 160 Member A2 is a protein involved in cellular processes. It has a mass of approximately 81 kDa. Researchers have found FAM160A2 expressed in various human tissues with notable presence in the brain and liver. The protein features a conserved region typical for this family suggesting a specific cellular role possibly related to protein-protein interactions.
Biological function summary

FAM160A2 contributes to cellular organization and homeostasis. It assists in regulating intracellular signaling pathways possibly working as part of larger protein complexes. This involvement in cellular signaling pathways implies that FAM160A2 plays a part in maintaining the normal function of cells. It can impact processes such as signal transduction and cellular communication though its precise biological functions remain under study.

Pathways

Research indicates that FAM160A2 participates in signaling cascades such as the MAPK pathway and the apoptosis pathway. Through the MAPK pathway it may act alongside proteins like ERK1/2 to regulate cellular responses to stimuli including stress and growth signals. In the apoptosis pathway FAM160A2's role possibly associates with proteins like Bcl-2 influencing cell death decisions which are critical for tissue development and immune response.

Scientific findings suggest FAM160A2's involvement in neurodegenerative diseases and some liver conditions. In neurodegeneration its interaction with proteins such as Tau could contribute to molecular mechanisms leading to neuronal dysfunction. In liver-related disorders FAM160A2 might connect with proteins involved in metabolic regulation indicating its role in conditions characterized by metabolic imbalance. Understanding these connections could guide future research and therapeutic strategies.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed : 32073997).
See full target information FHIP1B
style
left-column

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in aging neuroscience 12:591938 PubMed33304268

2020

1% Isoflurane and 1.2 μg/ml of Propofol: A Combination of Anesthetics That Causes the Least Damage to Hypoxic Neurons.

Applications

Unspecified application

Species

Unspecified reactive species

Xinyue Bu,Tang Li,Di Guo,Chenyi Yang,Jinxin Wang,Xinyi Wang,Zhuo Yang,Haiyun Wang

JCI insight 5: PubMed31094704

2019

Protective role of B cells in sterile particulate-induced lung injury.

Applications

Unspecified application

Species

Unspecified reactive species

Shaikh M Atif,Douglas G Mack,Amy S McKee,Javier Rangel-Moreno,Allison K Martin,Andrew Getahun,Lisa A Maier,John C Cambier,Rubin Tuder,Andrew P Fontenot
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB196026

Anti-Thrombopoietin antibody [EPR14948]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thrombopoietin antibody [EPR14948] (AB196026)

  • 0
  • 0
Primary Antibodies

AB205198

Anti-AACT antibody [EPR17088-68]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AACT antibody [EPR17088-68] (AB205198)

  • 0
  • 0
Primary Antibodies

AB181557

Anti-Oct4 antibody [EPR17929] - ChIP Grade

RabMAb|Advanced Validation|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-Oct4 antibody [EPR17929] - ChIP Grade (AB181557)

  • 5
  • 20
Primary Antibodies

AB180587

Anti-Peroxiredoxin 5 antibody [EPR14529(B)]

BOND RX™ Validated|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Peroxiredoxin 5 antibody [EPR14529(B)] (AB180587)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com