Rabbit Recombinant Monoclonal FAM160A2 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication.
Images
![Western blot - Anti-FAM160A2 antibody [EPR13604] - BSA and Azide free (AB250719), expandable thumbnail](https://content.abcam.com/products/images/fam160a2-antibody-epr13604-bsa-and-azide-free-ab250719--western-blot-img61594.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-FAM160A2 antibody [EPR13604] - BSA and Azide free (AB250719)")
Publications
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- Frontiers in aging neuroscience 12:59193820201% Isoflurane and 1.2 μg/ml of Propofol: A Combination of Anesthetics That Causes the Least Damage to Hypoxic Neurons.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXinyue Bu et. al.PubMed 33304268
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| WB | |
|---|---|
| Human | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
Target data
Function
Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed:32073997).
Alternative names
C11orf56, FAM160A2, KIAA1759, FHIP1B, FHF complex subunit HOOK-interacting protein 1B, FTS- and Hook-interacting protein, FHIP
Recommended products
Rabbit Recombinant Monoclonal FAM160A2 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Carrier free
- Yes
- Clone number
- EPR13604
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
- Storage information
- Do Not Freeze
Notes
ab250719 is the carrier-free version of Anti-FAM160A2 antibody [EPR13604] ab184160.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. The carrier-free buffer and high concentration allow for increased conjugation efficiency.
This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
FAM160A2 also known as Family with Sequence Similarity 160 Member A2 is a protein involved in cellular processes. It has a mass of approximately 81 kDa. Researchers have found FAM160A2 expressed in various human tissues with notable presence in the brain and liver. The protein features a conserved region typical for this family suggesting a specific cellular role possibly related to protein-protein interactions.
- Biological function summary
FAM160A2 contributes to cellular organization and homeostasis. It assists in regulating intracellular signaling pathways possibly working as part of larger protein complexes. This involvement in cellular signaling pathways implies that FAM160A2 plays a part in maintaining the normal function of cells. It can impact processes such as signal transduction and cellular communication though its precise biological functions remain under study.
- Pathways
Research indicates that FAM160A2 participates in signaling cascades such as the MAPK pathway and the apoptosis pathway. Through the MAPK pathway it may act alongside proteins like ERK1/2 to regulate cellular responses to stimuli including stress and growth signals. In the apoptosis pathway FAM160A2's role possibly associates with proteins like Bcl-2 influencing cell death decisions which are critical for tissue development and immune response.
- Associated diseases and disorders
Scientific findings suggest FAM160A2's involvement in neurodegenerative diseases and some liver conditions. In neurodegeneration its interaction with proteins such as Tau could contribute to molecular mechanisms leading to neuronal dysfunction. In liver-related disorders FAM160A2 might connect with proteins involved in metabolic regulation indicating its role in conditions characterized by metabolic imbalance. Understanding these connections could guide future research and therapeutic strategies.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
![Western blot - Anti-FAM160A2 antibody [EPR13604] - BSA and Azide free (ab250719), expandable thumbnail](https://content.abcam.com/products/images/fam160a2-antibody-epr13604-bsa-and-azide-free-ab250719--western-blot-img61594.jpg "Western blot - Anti-FAM160A2 antibody [EPR13604] - BSA and Azide free (ab250719)")
Western blot - Anti-FAM160A2 antibody [EPR13604] - BSA and Azide free (ab250719)
This data was developed using Anti-FAM160A2 antibody [EPR13604] ab184160, the same antibody clone in a different buffer formulation.
All lanes: Western blot - Anti-FAM160A2 antibody [EPR13604] (Anti-FAM160A2 antibody [EPR13604] ab184160) at 1/1000 dilution
Lane 1: HeLa lysate at 10 µg
Lane 2: Human fetal brain lysate at 10 µg
SecondaryAll lanes: Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 106 kDa
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