JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB254815

Anti-FAM168A antibody

Be the first to review this product! Submit a review

|

(2 Publications)

Rabbit Polyclonal FAM168A antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FAM168A aa 1-100.

View Alternative Names

KIAA0280, TCRP1, FAM168A, Protein FAM168A, Tongue cancer chemotherapy resistance-associated protein 1

5 Images
Immunocytochemistry/ Immunofluorescence - Anti-FAM168A antibody (AB254815)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-FAM168A antibody (AB254815)

PFA fixed, Triton X-100 permeabilized RH-30 (Human cell line) cells labeling FAM168A using ab254815 at 4µg/ml (green) in ICC/IF.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM168A antibody (AB254815)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM168A antibody (AB254815)

Paraffin-embedded human hippocampus tissue stained for FAM168A using ab254815 at 1/50 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM168A antibody (AB254815)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM168A antibody (AB254815)

Paraffin-embedded human cerebellum tissue stained for FAM168A using ab254815 at 1/50 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM168A antibody (AB254815)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM168A antibody (AB254815)

Paraffin-embedded human pancreas tissue stained for FAM168A using ab254815 at 1/50 dilution in immunohistochemical analysis. No positivity in exocrine glandular cells as expected.

Western blot - Anti-FAM168A antibody (AB254815)
  • WB

Supplier Data

Western blot - Anti-FAM168A antibody (AB254815)

Lane 1:

Western blot - Anti-FAM168A antibody (ab254815)

Lane 2:

Western blot - Anti-FAM168A antibody (ab254815) at 0.4 µg/mL

Lane 1:

DNA Ladder

Lane 2:

SK-MEL-30 cell lysate

Predicted band size: 26 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human FAM168A aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q92567

style
left-column

Complementary Products

Secondary Antibodies

AB150155

Donkey Anti-Rat IgG H&L (Alexa Fluor® 647) preadsorbed

Immunocytochemistry/ Immunofluorescence - Donkey Anti-Rat IgG H&L (Alexa Fluor® 647) preadsorbed (AB150155)

  • 5
  • 2
Secondary Antibodies

AB205721

Goat Anti-Chicken IgY H&L (HRP)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Goat Anti-Chicken IgY H&L (HRP) (AB205721)

  • 3
  • 1
Proteins & Peptides

AB280753

Recombinant Human PD1 protein

Mass Spectrometry - Recombinant Human PD1 protein (AB280753)

  • 0
  • 0
Proteins & Peptides

AB217407

Recombinant human Vitronectin/S-Protein (Animal Free)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FAM168A also known as XTP8 functions as a protein involved in cellular processes that are still being fully elucidated. The protein mass is approximately 22 kDa. It is expressed in several tissues including the brain and testis suggesting roles in neural and reproductive systems. Researchers focus on its mechanical action due to its interaction with other cellular components indicating a part in critical cellular mechanisms.
Biological function summary

FAM168A participates in regulating gene expression and possibly signaling pathways. While it does not appear as part of a specific complex it associates with cell growth and apoptosis regulation. Studies suggest its influence during cell development stages marking its importance in maintaining cellular homeostasis.

Pathways

FAM168A displays involvement in the regulation of apoptosis and the cell cycle. It potentially interacts with pathways like the PI3K/AKT and MAPK which control cell survival and growth. The protein links with components such as AKT1 and ERK1/2 contributing to our understanding of its functional network in the cell.

Research associates FAM168A with neurological conditions and cancer. Gene expression alterations relate it with disorders like schizophrenia affecting proteins such as DISC1. Its roles extend to oncological studies where it interacts with other proteins like p53 hinting at tumor growth implications and necessitating further exploration in disease contexts.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

In cancer context, protects cells from induced-DNA damage and apoptosis. Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation. Decreases POLB ubiquitation and stabilizes its protein levels.
See full target information FAM168A
style
left-column

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Cell death & disease 14:212 PubMed36966163

2023

ZNF582 overexpression restrains the progression of clear cell renal cell carcinoma by enhancing the binding of TJP2 and ERK2 and inhibiting ERK2 phosphorylation.

Applications

Unspecified application

Species

Unspecified reactive species

Wuping Yang,Zedan Zhang,Lei Li,Kenan Zhang,Yawei Xu,Mancheng Xia,Jingcheng Zhou,Yanqing Gong,Jinchao Chen,Kan Gong

Oncogenesis 11:19 PubMed35459265

2022

TCRP1 activated by mutant p53 promotes NSCLC proliferation via inhibiting FOXO3a.

Applications

Unspecified application

Species

Unspecified reactive species

Hao Liu,Xiaoting Jia,Kai Luo,Xiangzhou Chen,Zhijie Zhang,Danyang Chen,Yixue Gu,Zhimin He,Guopei Zheng
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com