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Rabbit Polyclonal FAM172A antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 8 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ARB2A aa 1-150.

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Images

Immunocytochemistry/ Immunofluorescence - Anti-FAM172A antibody (AB121364), expandable thumbnail

Publications

Key facts

Isotype
IgG
Host species
Rabbit
Storage buffer

pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)

Form
Liquid
Clonality
Polyclonal

Immunogen

  • Recombinant Fragment Protein within Human ARB2A aa 1-150. The exact immunogen used to generate this antibody is proprietary information. Database link Q8WUF8

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
ICC/IF
Human
Tested
Mouse
Predicted
Rat
Predicted

Tested
Tested

Species
Human
Dilution info
0.25000-2.00000 µg/mL
Notes

-

Predicted
Predicted

Species
Mouse, Rat
Dilution info
-
Notes

-

Target data

Function

Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity.

Alternative names

Recommended products

Rabbit Polyclonal FAM172A antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 8 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ARB2A aa 1-150.

Key facts

Isotype
IgG
Form
Liquid
Clonality
Polyclonal
Immunogen
  • Recombinant Fragment Protein within Human ARB2A aa 1-150. The exact immunogen used to generate this antibody is proprietary information. Database link Q8WUF8
Purification technique
Affinity purification Immunogen
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.
Activity summary

FAM172A also known as KIAA1690 is a protein that plays a significant role in the human body. It has an approximate molecular mass of 72 kDa. Researchers find FAM172A expression in various tissues indicating active participation in multiple cellular processes. Due to its widespread presence it attracts much interest in functional studies although specific details about its biochemical activity remain under investigation.

Biological function summary

The protein encoded by FAM172A participates in the cellular maintenance processes. While not conclusively part of any known complex its interactions suggest a regulatory role potentially in nucleic acid binding or cellular signaling processes. Studies also show its presence at the transcriptional level in cells indicating an influence on gene expression.

Pathways

FAM172A potentially connects to important cellular signaling pathways including the PI3K-Akt pathway. This pathway is important for cell survival and proliferation. Additionally FAM172A shows interaction tendencies with proteins like Akt1 reinforcing its participation in signaling networks that maintain cellular health and function.

Associated diseases and disorders

FAM172A has associations with conditions like cancer. Its role in cellular growth pathways suggests that mutations or dysregulation of FAM172A might contribute to oncogenesis. Connections to proteins involved in cancer-related pathways including mTOR indicate potential targets for therapeutic intervention. Researchers continue to investigate how alterations in FAM172A expression or function contribute to disease states aiming for new treatment strategies.

Product promise

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1 product image

  • Immunocytochemistry/ Immunofluorescence - Anti-FAM172A antibody (ab121364), expandable thumbnail

    Immunocytochemistry/ Immunofluorescence - Anti-FAM172A antibody (ab121364)

    Immunocytochemistry analysis of U-251 MG (human brain glioma cell line) cells labelling FAM172A with ab121364 at 2 μg/mL.

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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