Rabbit Polyclonal FAM172A antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 8 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ARB2A aa 1-150.
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
ICC/IF | |
---|---|
Human | Tested |
Mouse | Predicted |
Rat | Predicted |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 0.25000-2.00000 µg/mL | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Mouse, Rat | Dilution info - | Notes - |
Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity.
C5orf21, FAM172A, ARB2A, Cotranscriptional regulator ARB2A, ARB2 cotranscriptional regulator A, Cotranscriptional regulator FAM172A, Protein FAM172A
Rabbit Polyclonal FAM172A antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 8 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ARB2A aa 1-150.
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
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FAM172A also known as KIAA1690 is a protein that plays a significant role in the human body. It has an approximate molecular mass of 72 kDa. Researchers find FAM172A expression in various tissues indicating active participation in multiple cellular processes. Due to its widespread presence it attracts much interest in functional studies although specific details about its biochemical activity remain under investigation.
The protein encoded by FAM172A participates in the cellular maintenance processes. While not conclusively part of any known complex its interactions suggest a regulatory role potentially in nucleic acid binding or cellular signaling processes. Studies also show its presence at the transcriptional level in cells indicating an influence on gene expression.
FAM172A potentially connects to important cellular signaling pathways including the PI3K-Akt pathway. This pathway is important for cell survival and proliferation. Additionally FAM172A shows interaction tendencies with proteins like Akt1 reinforcing its participation in signaling networks that maintain cellular health and function.
FAM172A has associations with conditions like cancer. Its role in cellular growth pathways suggests that mutations or dysregulation of FAM172A might contribute to oncogenesis. Connections to proteins involved in cancer-related pathways including mTOR indicate potential targets for therapeutic intervention. Researchers continue to investigate how alterations in FAM172A expression or function contribute to disease states aiming for new treatment strategies.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
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Immunocytochemistry analysis of U-251 MG (human brain glioma cell line) cells labelling FAM172A with ab121364 at 2 μg/mL.
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