AB167180

Anti-FAM60A antibody

Name: Anti-FAM60A antibody (ab167180) | Abcam
Brand: Abcam Limited
SKU: AB167180

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(5 Publications)

Mouse Polyclonal FAM60A antibody. Carrier free. Suitable for WB and reacts with Transfected cell lysate samples. Cited in 5 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human SINHCAF.

View Alternative Names

C12orf14, FAM60A, L4, SINHCAF, SIN3-HDAC complex-associated factor, Protein FAM60A, Tera protein homolog

1 Images

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Western blot - Anti-FAM60A antibody (AB167180)

All lanes:

Western blot - Anti-FAM60A antibody (ab167180) at 1/500 dilution

Lane 1:

FAM60A transfected 293T cell line lysate at 15 µL

Lane 2:

Non-transfected 293T cell line lysate at 15 µL

Predicted band size: 25 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Applications

applications

Immunogen

Recombinant Full Length Protein corresponding to Human SINHCAF.

Q9NP50

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Transfected cell lysate": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2500", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (PubMed : 22865885, PubMed : 22984288). Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is essential for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming (By similarity).

See full target information SINHCAF

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Cancer medicine 12:17491-17503 PubMed37439040

2023

FAM60A promotes osteosarcoma development and progression.

Applications

Unspecified application

Species

Unspecified reactive species

Yu Sun,Yu-Nan Man,Jin-Hui Cheng,Jing-Tang Li,Ya-Yun Liu

Biomedical journal 46:100528 PubMed35358714

2022

Trafficking protein TMED3 promotes esophageal squamous cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yuxian Yang,Shiliang Liu,Chunxia Xie,Qiaoqiao Li,Tiantian Gao,Mengzhong Liu,Mian Xi,Lei Zhao

Translational oncology 14:101196 PubMed34388694

2021

Loss of FAM60A attenuates cell proliferation in glioma via suppression of PI3K/Akt/mTOR signaling pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaocen Liu,Mengying Zhang,Xiaolong Zhu,Yingying Wang,Kun Lv,Hui Yang

Biochemical and biophysical research communications 521:1003-1009 PubMed31727367

2019

FAM60A, increased by Helicobacter pylori, promotes proliferation and suppresses apoptosis of gastric cancer cells by targeting the PI3K/AKT pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Xinjie Yao,Dongyan Liu,Linyan Zhou,Ying Xie,Yan Li

Scientific reports 7:42060 PubMed28169357

2017

Integrative analysis of copy number and transcriptional expression profiles in esophageal cancer to identify a novel driver gene for therapy.

Applications

Unspecified application

Species

Unspecified reactive species

Gaochao Dong,Qixing Mao,Decai Yu,Yi Zhang,Mantang Qiu,Gaoyue Dong,Qiang Chen,Wenjie Xia,Jie Wang,Lin Xu,Feng Jiang

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-FAM60A antibody

Western blot - Anti-FAM60A antibody (AB167180)

Key facts

Host species

Clonality

Isotype

Carrier free

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (5)

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Product promise