Mouse Polyclonal FAM60A antibody. Carrier free. Suitable for WB and reacts with Transfected cell lysate samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human SINHCAF.
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Publications
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- Biomedical journal 46:1005282022Trafficking protein TMED3 promotes esophageal squamous cell carcinoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYuxian Yang,Shiliang Liu,Chunxia Xie,Qiaoqiao Li,Tiantian Gao,Mengzhong Liu,Mian Xi,Lei ZhaoPubMed 35358714
- Translational oncology 14:1011962021Loss of FAM60A attenuates cell proliferation in glioma via suppression of PI3K/Akt/mTOR signaling pathways.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiaocen Liu,Mengying Zhang,Xiaolong Zhu,Yingying Wang,Kun Lv,Hui YangPubMed 34388694
- Biochemical and biophysical research communications 521:1003-10092019FAM60A, increased by Helicobacter pylori, promotes proliferation and suppresses apoptosis of gastric cancer cells by targeting the PI3K/AKT pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXinjie Yao,Dongyan Liu,Linyan Zhou,Ying Xie,Yan LiPubMed 31727367
- Scientific reports 7:420602017Integrative analysis of copy number and transcriptional expression profiles in esophageal cancer to identify a novel driver gene for therapy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGaochao Dong et. al.PubMed 28169357
Key facts
- Isotype
- IgG
- Host species
- Mouse
- Storage buffer
pH: 7.4
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Full Length Protein corresponding to Human SINHCAF. Database link Q9NP50
Reactivity data
Select an application| WB | |
|---|---|
| Transfected cell lysate | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Transfected cell lysate | Dilution info 1/500.00000 - 1/2500.00000 | Notes - |
Target data
Function
Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (PubMed:22865885, PubMed:22984288). Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is essential for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming (By similarity).
Alternative names
C12orf14, FAM60A, L4, SINHCAF, SIN3-HDAC complex-associated factor, Protein FAM60A, Tera protein homolog
Recommended products
Mouse Polyclonal FAM60A antibody. Carrier free. Suitable for WB and reacts with Transfected cell lysate samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human SINHCAF.
Key facts
- Isotype
- IgG
- Host species
- Mouse
- Storage buffer
pH: 7.4
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Full Length Protein corresponding to Human SINHCAF. Database link Q9NP50
- Carrier free
- Yes
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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1 product image
Western blot - Anti-FAM60A antibody (ab167180)
All lanes: Western blot - Anti-FAM60A antibody (ab167180) at 1/500 dilution
Lane 1: FAM60A transfected 293T cell line lysate at 15 µL
Lane 2: Non-transfected 293T cell line lysate at 15 µL
Predicted band size: 25 kDa
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Product protocols
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