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AB122175

Anti-FAM83B antibody

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(2 Publications)

Rabbit Polyclonal FAM83B antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FAM83B aa 500-650.

View Alternative Names

C6orf143, FAM83B, Protein FAM83B

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM83B antibody (AB122175)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM83B antibody (AB122175)

ab122175 at 1/200 dilution staining FAM83B in Paraffin-embedded Human Duodenum tissue by Immunohistochemistry.

Immunocytochemistry/ Immunofluorescence - Anti-FAM83B antibody (AB122175)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-FAM83B antibody (AB122175)

Immunofluorescent staining of Human cell line U-251 MG shows positivity in nucleus but not nucleoli and vesicles. Recommended concentration of ab122175 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human FAM83B aa 500-650. The exact immunogen used to generate this antibody is proprietary information.

Q5T0W9

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1-4 µg/mL", "ICCIF-species-notes": "<p>Recommend PFA Fixation and Triton X-100 treatment</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.
See full target information FAM83B
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

International journal of oncology 64: PubMed38426627

2024

Characterization of KIF20B as a novel prognostic biomarker and therapeutic target for breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Regina Wachuka Mbugua,Atsushi Takano,Bayarbat Tsevegjav,Tomoyuki Yokose,Toshinari Yamashita,Yohei Miyagi,Yataro Daigo

Biomedicine & pharmacotherapy = Biomedecine & phar 115:108939 PubMed31079003

2019

Knocking down FAM83B inhibits endometrial cancer cell proliferation and metastasis by silencing the PI3K/AKT/mTOR pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Qiongyan Lin,Hui Chen,Minfen Zhang,Hanzhen Xiong,Qingping Jiang
View all publications
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Product promise

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