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AB126938

Anti-FAM84A antibody

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(1 Publication)

Rabbit Polyclonal FAM84A antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human LRATD1 aa 1-250.

View Alternative Names

FAM84A, NSE1, LRATD1, Protein LRATD1, LRAT domain-containing 1, Neurologic sensory protein 1, Protein FAM84A

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-FAM84A antibody (AB126938)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-FAM84A antibody (AB126938)

ab126938, at 1/500 dilution, staining FAM84A in methanol-fixed A431 cells by Immunofluorescence. The lower image is co-stained with Hoechst 33342.

Western blot - Anti-FAM84A antibody (AB126938)
  • WB

Unknown

Western blot - Anti-FAM84A antibody (AB126938)

12% SDS PAGE

All lanes:

Western blot - Anti-FAM84A antibody (ab126938) at 1/1000 dilution

All lanes:

IMR32 whole cell lysate at 30 µg

Predicted band size: 32 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human LRATD1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.

Q96KN4

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/500", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FAM84A also known as Family with Sequence Similarity 84 Member A is a protein that plays a role in specific mechanical functions within cells. It has a molecular mass of approximately 24 kDa. This protein is expressed in several tissues with higher expression levels seen in certain carcinoma cell lines. It is frequently found in epithelial tissues indicating its potential involvement in various cellular processes related to these locations.
Biological function summary

Research indicates that FAM84A influences cellular proliferation and migration contributing to normal cell growth and possibly carcinogenic processes. This protein does not associate with any well-defined complex but seems to perform its functions independently or in collaboration with other binding partners yet to be identified. Its role suggests that FAM84A may be important in maintaining cellular architecture and promoting cellular movement especially within epithelial environments.

Pathways

Current studies suggest that FAM84A interacts with cellular pathways associated with cell cycle progression and cancer metastasis. These pathways regulate cell division and expansion contributing to the spread of cancerous cells. FAM84A also shows potential associations with signaling molecules that manage cell motility such as cadherins although direct links in these pathways need more exploration.

FAM84A has been linked to cancer particularly colorectal cancer and prostate cancer. Its upregulation correlates with tumor aggressiveness highlighting its potential as a biomarker for these malignancies. FAM84A also shows interactions with proteins such as p53 which is central to the regulation of cell cycle and apoptosis further supporting its relevance in cancer pathophysiology. Understanding these associations helps in exploring therapeutic approaches targeting FAM84A in certain cancers.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May play a role in cell morphology and motility.
See full target information LRATD1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Scientific reports 11:22764 PubMed34815513

2021

Nanoplasmonic immunosensor for the detection of SCG2, a candidate serum biomarker for the early diagnosis of neurodevelopmental disorder.

Applications

Unspecified application

Species

Unspecified reactive species

So-Hee Lim,Yun-Ju Sung,Narae Jo,Na-Yoon Lee,Kyoung-Shim Kim,Da Yong Lee,Nam-Soon Kim,Jeehun Lee,Ju-Young Byun,Yong-Beom Shin,Jae-Ran Lee
View all publications
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Product promise

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