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AB204083

Anti-FAM98A antibody

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(4 Publications)

Rabbit Polyclonal FAM98A antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FAM98A aa 1-150.

View Alternative Names

Protein FAM98A, FAM98A

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM98A antibody (AB204083)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM98A antibody (AB204083)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Human Nasopharynx tissue labelling FAM98A with ab204083 at 1/20 dilution.

Immunocytochemistry/ Immunofluorescence - Anti-FAM98A antibody (AB204083)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-FAM98A antibody (AB204083)

Immunofluorescent staining of PFA/Triton X-100 fixed/permeabilized A431 cells labeling FAM98A with ab204083 at 4 μg/ml (green).

Western blot - Anti-FAM98A antibody (AB204083)
  • WB

Unknown

Western blot - Anti-FAM98A antibody (AB204083)

All lanes:

Western blot - Anti-FAM98A antibody (ab204083) at 0.4 µg/mL

All lanes:

Human cell line HEL

Predicted band size: 55 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human FAM98A aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

Q8NCA5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FAM98A also known as Family with Sequence Similarity 98 Member A is a cytoplasmic protein with a mass of approximately 26 kDa. This protein shows expression in various tissues including the brain and liver. It functions mechanically in processes involving RNA contributing to RNA-binding activities although the specific details of its RNA interactions remain to be fully understood.
Biological function summary

This protein acts within a larger multi-protein complex affecting cellular and molecular functions that are important for proper cell regulation. It participates in processes like gene expression modulation although the precise scope of its biological roles is still under investigation. FAM98A also appears to engage in interactions influencing cell cycle regulation which highlights its importance in maintaining cell stability.

Pathways

FAM98A integrates into significant cellular pathways such as TOR signaling and may also influence mitotic processes. It interacts with proteins like the RACK1 scaffolding protein suggesting a role in protein translation and signaling pathways. These interactions position FAM98A within important circuits that oversee cell growth and proliferation.

Changes in FAM98A function or expression could contribute to cancer and neurological disorders reflecting its involvement in cell cycle and regulatory processes. For instance in certain cancers its altered interaction with proteins like RACK1 may impact tumor progression. Meanwhile in neurological disorders disruptions in its RNA-binding role might link to dysregulation of neuronal functions. Further research could open additional insights into these associations.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Positively stimulates PRMT1-induced protein arginine methylation (PubMed : 28040436). Involved in skeletal homeostasis (By similarity). Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity).
See full target information FAM98A
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Nucleic acids research 53: PubMed40557872

2025

Nonredundant roles of topoisomerase 2α and 2β in the cytosolic replication of vaccinia virus.

Applications

Unspecified application

Species

Unspecified reactive species

Ilaria Dalla Rosa,Lois Kent,Michael Way

Journal of gynecologic oncology 33:e2 PubMed34783205

2021

Circular RNA intraflagellar transport 80 facilitates endometrial cancer progression through modulating miR-545-3p/FAM98A signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Na Wang,Yunfeng Guo,Liqin Song,Tong Tong,Xiaomei Fan

Oncology letters 21:367 PubMed33747224

2021

MicroRNA-26a inhibits cell proliferation and invasion by targeting FAM98A in breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Tan Liu,Ziming Wang,Menghao Dong,Jingjing Wei,Yueyin Pan

Cancer management and research 10:2269-2278 PubMed30100758

2018

FAM98A promotes proliferation of non-small cell lung cancer cells via the P38-ATF2 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Rui Zheng,Quanbo Liu,Tianxu Wang,Lili Wang,Yong Zhang
View all publications
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