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AB54411

Anti-Fc epsilon RI/FCER1A antibody [9E1]

4

(6 Reviews)

|

(7 Publications)

Anti-Fc epsilon RI/FCER1A antibody [9E1] (ab54411) is a mouse monoclonal antibody detecting Fc epsilon RI/FCER1A in Western Blot, Flow Cytometry, IP, IHC-P, ICC/IF, ELISA. Suitable for Human.

- Trusted since 2007

View Alternative Names

FCE1A, FCER1A, High affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, IgE Fc receptor subunit alpha, FcERI

1 Images
Flow Cytometry - Anti-Fc epsilon RI/FCER1A antibody [9E1] (AB54411)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-Fc epsilon RI/FCER1A antibody [9E1] (AB54411)

Staining of human peripheral blood cells with ab54411, showing staining of eosinophils.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

9E1

Isotype

IgG2b

Carrier free

No

Reacts with

Human

Applications

Flow Cyt, IHC-P, ELISA, WB, IP, ICC/IF

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

This antibody recognizes the human high affinity Fc receptor for IgE (Fc epsilon R1), which plays a central role in the IgE-mediated allergic response. Fc epsilon R1 consists of four subunits, a high affinity IgE binding alpha subunit, a beta chain and two di-sulphide linked gamma subunits. Clone 9E1 specifically recognizes the extracellular D1 domain of the Fc epsilon R1 alpha chain.

Reactivity data

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Product details

What is this antibody validated in?
Anti-Fc epsilon RI/FCER1A antibody [9E1] (ab54411) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA in Human samples.

Reviewed by scientists
Anti-Fc epsilon RI/FCER1A [9E1] (ab54411) has over 5 independent reviews from customers.

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Storage buffer
pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions.
See full target information FCER1A

Publications (7)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 23: PubMed35054842

2022

Dietary Exposure to Flame Retardant Tris (2-Butoxyethyl) Phosphate Altered Neurobehavior and Neuroinflammatory Responses in a Mouse Model of Allergic Asthma.

Applications

Unspecified application

Species

Unspecified reactive species

Tin-Tin Win-Shwe,Rie Yanagisawa,Thet-Thet Lwin,Fumitaka Kawakami,Eiko Koike,Hirohisa Takano

The Journal of allergy and clinical immunology 148:813-821.e7 PubMed33865872

2021

Small intestinal immunopathology and GI-associated antibody formation in hereditary alpha-tryptasemia.

Applications

Unspecified application

Species

Unspecified reactive species

Liza Konnikova,Tanya O Robinson,Anna H Owings,James F Shirley,Elisabeth Davis,Ying Tang,Sarah Wall,Jian Li,Mohammad H Hasan,Raad Z Gharaibeh,Lybil B Mendoza Alvarez,Lisa K Ryan,Andria Doty,Jack F Chovanec,Michael P O'Connell,Dianne E Grunes,William P Daley,Emeran Mayer,Lin Chang,Julia Liu,Scott B Snapper,Joshua D Milner,Sarah C Glover,Jonathan J Lyons

Pharmaceutics 13: PubMed33917842

2021

Pre-Emptive Priming of Human Skin Improves Cutaneous Scarring and Is Superior to Immediate and Delayed Topical Anti-Scarring Treatment Post-Wounding: A Double-Blind Randomised Placebo-Controlled Clinical Trial.

Applications

Unspecified application

Species

Unspecified reactive species

Sara Ud-Din,Traci A Wilgus,Douglas D McGeorge,Ardeshir Bayat

JCI insight 4: PubMed31092735

2019

Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis.

Applications

Unspecified application

Species

Unspecified reactive species

Dennis G Moledina,F Perry Wilson,Jordan S Pober,Mark A Perazella,Nikhil Singh,Randy L Luciano,Wassim Obeid,Haiqun Lin,Michael Kuperman,Gilbert W Moeckel,Michael Kashgarian,Lloyd G Cantley,Chirag R Parikh

Scientific reports 8:4656 PubMed29545608

2018

Mast Cells Exhibiting Strong Cytoplasmic Staining for IgE and High Affinity IgE Receptor are Increased in IgG4-Related Disease.

Applications

Unspecified application

Species

Unspecified reactive species

Kenji Nishida,Yuka Gion,Mai Takeuchi,Takehiro Tanaka,Tatsuki R Kataoka,Tadashi Yoshino,Yasuharu Sato

PloS one 9:e107725 PubMed25255430

2014

Human eosinophils express the high affinity IgE receptor, FcεRI, in bullous pemphigoid.

Applications

Unspecified application

Species

Unspecified reactive species

Kelly N Messingham,Heather M Holahan,Alexandra S Frydman,Colleen Fullenkamp,Rupasree Srikantha,Janet A Fairley

PloS one 8:e64105 PubMed23734186

2013

Functional interaction of cockroach allergens and mannose receptor (CD206) in human circulating fibrocytes.

Applications

Flow Cyt

Species

Human

Ying-Ming Tsai,Shih-Chang Hsu,Jian Zhang,Yu-Feng Zhou,Beverly Plunkett,Shau-Ku Huang,Pei-Song Gao
View all publications

Product promise

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