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AB171278

Anti-Fc epsilon RI/FCER1A antibody [AER-37 (CRA1)] - Low endotoxin, Azide free

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(1 Publication)

Mouse Monoclonal Fc epsilon RI/FCER1A antibody. Carrier free. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Human FCER1A.

View Alternative Names

FCE1A, FCER1A, High affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, IgE Fc receptor subunit alpha, FcERI

1 Images
Flow Cytometry - Anti-Fc epsilon RI/FCER1A antibody [AER-37 (CRA1)] - Low endotoxin, Azide free (AB171278)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-Fc epsilon RI/FCER1A antibody [AER-37 (CRA1)] - Low endotoxin, Azide free (AB171278)

Flow cytometric analysis of Human lysed whole blood with Mouse IgG2b Isotype Control (green histogram) or 1 μg ab171278 (blue histogram) followed by Anti-Mouse IgG Biotin and Streptavidin PE. Cells in the lymphocyte gate were used for analysis.

  • 660 APC

    APC Anti-Fc epsilon RI/FCER1A antibody [AER-37 (CRA1)]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

AER-37 (CRA1)

Isotype

IgG2b

Light chain type

kappa

Carrier free

Yes

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Native Full Length Protein corresponding to Human FCER1A.

P12319

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1 µg for 10^5-10^8 Cells", "FlowCyt-species-notes": "<p>(in a final volume of 100 μl).</p><p><a href='/en-us/products/primary-antibodies/mouse-igg2b-kappa-monoclonal-7e10g10-isotype-control-ab170192'>ab170192</a> - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.</p>" } } }

Product details

Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by the LAL assay.

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.2 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions.
See full target information FCER1A

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Particle and fibre toxicology 13:16 PubMed27026438

2016

Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation.

Applications

Unspecified application

Species

Unspecified reactive species

Yusuke Hiraku,Feiye Guo,Ning Ma,Tatsuhiko Yamada,Shumin Wang,Shosuke Kawanishi,Mariko Murata
View all publications

Product promise

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