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AB288427

Anti-Fc epsilon RI/FCER1A antibody [Mar-1]

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(1 Publication)

Rabbit Recombinant Monoclonal Fc epsilon RI/FCER1A antibody. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 1 publication.

View Alternative Names

FCE1A, FCER1A, High affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, IgE Fc receptor subunit alpha, FcERI

1 Images
Flow Cytometry - Anti-Fc epsilon RI/FCER1A antibody [Mar-1] (AB288427)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-Fc epsilon RI/FCER1A antibody [Mar-1] (AB288427)

Flow cytometric analysis of mouse splenocytes stained with ab288427 at 1/100 dilution for 1 hour. Mouse splenocytes were stained with ab288427 (Blue line) or anti-Fluorescein IgG antibody (Isotype control, black line). After washing, bound antibody was detected using a goat anti-rabbit IgG AlexaFluor® 488 antibody at a dilution of 1 : 1000 and cells analyzed using a FACSCanto flow-cytometer.

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

Mar-1

Isotype

IgG

Light chain type

lambda

Carrier free

No

Reacts with

Mouse

Applications

Flow Cyt

applications

Specificity

This antibody specifically targets the non-signalling alpha chain of the FceR1 complex.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/100", "FlowCyt-species-notes": "<p></p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
Preservative: 0.02% Proclin 300 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions.
See full target information FCER1A

Publications (1)

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The Journal of investigative dermatology 122:1165-74 PubMed15140219

2004

A model system using tape stripping for characterization of Langerhans cell-precursors in vivo.

Applications

Unspecified application

Species

Unspecified reactive species

Sandra Holzmann,Christoph H Tripp,Matthias Schmuth,Katrin Janke,Franz Koch,Sem Saeland,Patrizia Stoitzner,Nikolaus Romani
View all publications

Product promise

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