Rabbit Polyclonal Ferritin Heavy Chain antibody. Suitable for WB, IHC-P and reacts with Pig, Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Pig FTH1.
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Publications
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- Microbiology spectrum 11:e01906222023Characterization of Gut Microbiota Compositions along the Intestinal Tract in Double Knockout Piglets and Their Potential Roles in Iron Absorption.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiu-Ling Zhang,Yan-Rong Zhou,Song-Song Xu,Si Xu,Yu-Jian Xiong,Kui Xu,Chang-Jiang Xu,Jing-Jing Che,Lei Huang,Zhi-Guo Liu,Bing-Yuan Wang,Yu-Lian Mu,Shao-Bo Xiao,Kui LiPubMed 36625575
- Nutrients 14:2022Iron Deficiency and Overload Modulate the Inflammatory Responses and Metabolism of Alveolar Macrophages.Applications:Unspecified applicationReactive species:Unspecified reactive speciesVivian Perng,Shya E Navazesh,Jungjae Park,Joseph R Arballo,Peng JiPubMed 35956279
- Cell death & disease 12:2202021Sunitinib treatment promotes metastasis of drug-resistant renal cell carcinoma via TFE3 signaling pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLuchao Li,Shuo Zhao,Zhengfang Liu,Nianzhao Zhang,Shuo Pang,Jikai Liu,Cheng Liu,Yidong FanPubMed 33637706
- The Journal of nutrition 149:398-4052019Iron Oversupplementation Causes Hippocampal Iron Overloading and Impairs Social Novelty Recognition in Nursing Piglets.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPeng Ji,Bo Lönnerdal,Kwangwook Kim,Cynthia N JinnoPubMed 30624730
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Full Length Protein corresponding to Pig FTH1. Database link P19130
Consider this alternative
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Expected |
| Pig | Tested | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Pig | Dilution info 0.2-2 µg/mL | Notes - |
Species Human | Dilution info 0.2-2 µg/mL | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Pig | Dilution info 5-20 µg/mL | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
Associated Products
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Target data
Function
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed:9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed:9003196). Also plays a role in delivery of iron to cells (By similarity). Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed:24695223, PubMed:26436293).
Alternative names
FTH, FTHL6, OK/SW-cl.84, PIG15, FTH1, Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 protein
Recommended products
Rabbit Polyclonal Ferritin Heavy Chain antibody. Suitable for WB, IHC-P and reacts with Pig, Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Pig FTH1.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Full Length Protein corresponding to Pig FTH1. Database link P19130
- Purification technique
- Affinity purification Immunogen
- Concentration
- Purification notes
ab231253 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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7 product images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferritin Heavy Chain antibody (ab231253)
Paraffin-embedded pig spleen tissue stained for Ferritin Heavy Chain with ab231253 at 20 μg/ml in immunohistochemical analysis. DAB staining.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferritin Heavy Chain antibody (ab231253)
Paraffin-embedded pig kidney tissue stained for Ferritin Heavy Chain with ab231253 at 20 μg/ml in immunohistochemical analysis. DAB staining.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ferritin Heavy Chain antibody (ab231253)
Paraffin-embedded pig liver tissue stained for Ferritin Heavy Chain with ab231253 at 20 μg/ml in immunohistochemical analysis. DAB staining.
Western blot - Anti-Ferritin Heavy Chain antibody (ab231253)
All lanes: Western blot - Anti-Ferritin Heavy Chain antibody (ab231253) at 2 µg/mL
All lanes: U-87 MG (human glioblastoma-astrocytoma epithelial cell line) cell lysate
Predicted band size: 21 kDa
Western blot - Anti-Ferritin Heavy Chain antibody (ab231253)
All lanes: Western blot - Anti-Ferritin Heavy Chain antibody (ab231253) at 2 µg/mL
All lanes: Pig cerebrum lysate
Predicted band size: 20 kDa, 21 kDa, 25 kDa, 26 kDa, 28 kDa, 29 kDa, 31 kDa, 38 kDa
Western blot - Anti-Ferritin Heavy Chain antibody (ab231253)
All lanes: Western blot - Anti-Ferritin Heavy Chain antibody (ab231253) at 2 µg/mL
All lanes: Pig liver lysate
Predicted band size: 21 kDa, 23 kDa, 26 kDa, 45 kDa, 78 kDa
Western blot - Anti-Ferritin Heavy Chain antibody (ab231253)
All lanes: Western blot - Anti-Ferritin Heavy Chain antibody (ab231253) at 2 µg/mL
All lanes: Recombinant pig Ferritin Heavy Chain protein
Predicted band size: 21 kDa
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