AB69090

Anti-Ferritin Light Chain antibody

Name: Anti-Ferritin Light Chain antibody (ab69090) | Abcam
Brand: Abcam Limited
SKU: AB69090
Price: 180 USD
Availability: InStock
Rating: 5 (34 reviews)

(34 Reviews)

(140 Publications)

Anti-Ferritin Light Chain antibody (ab69090) is a rabbit polyclonal antibody detecting Ferritin Light Chain in Western Blot. Suitable for Human, Mouse, Rat.

- Over 90 publications
- Trusted since 2009

View Alternative Names

Ferritin light chain, Ferritin L subunit, FTL

1 Images

Project

Western blot - Anti-Ferritin Light Chain antibody (AB69090)

All lanes:

Western blot - Anti-Ferritin Light Chain antibody (ab69090) at 1 µg/mL

Lane 1:

Human liver tissue lysate - total protein (<a href='/en-us/products/unavailable/human-liver-tissue-lysate-total-protein-ab29889'>ab29889</a>) at 10 µg

Lane 2:

Liver (Rat) Tissue Lysate at 10 µg

Lane 3:

Western blot - Mouse spleen tissue lysate - total protein (<a href='/en-us/products/tissue-lysates/mouse-spleen-tissue-lysate-total-protein-ab29293'>ab29293</a>) at 10 µg

Lane 4:

Testis (Rat) Tissue Lysate - normal tissue (<a href='/en-us/products/unavailable/testis-rat-tissue-lysate-normal-tissue-ab29388'>ab29388</a>) at 10 µg

Lane 5:

Liver (Mouse) Tissue Lysate at 10 µg

Lane 6:

Ovary (Mouse) Tissue Lysate at 10 µg

Secondary

All lanes:

Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Predicted band size: 20 kDa

Observed band size: 20 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

WB, IHC-FoFr

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

From Jan 2024, QC testing of replenishment batches of this polyclonal changed. All tested and expected application and reactive species combinations are still covered by our Abcam product promise. However, we no longer test all applications. For more information on a specific batch, please contact our Scientific Support who will be happy to help.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCFoFr" : {"fullname" : "Immunohistochemistry (PFA perfusion fixed frozen sections)", "shortname":"IHC-FoFr"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "0.5-1 µg/mL", "WB-species-notes": "", "IHCFoFr-species-checked": "guaranteed", "IHCFoFr-species-dilution-info": "1 µg/mL", "IHCFoFr-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "0.5-1 µg/mL", "WB-species-notes": "", "IHCFoFr-species-checked": "guaranteed", "IHCFoFr-species-dilution-info": "1 µg/mL", "IHCFoFr-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-1 µg/mL", "WB-species-notes": "", "IHCFoFr-species-checked": "guaranteed", "IHCFoFr-species-dilution-info": "1 µg/mL", "IHCFoFr-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCFoFr-species-checked": "predicted", "IHCFoFr-species-dilution-info": "", "IHCFoFr-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCFoFr-species-checked": "predicted", "IHCFoFr-species-dilution-info": "", "IHCFoFr-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Product details

What is this antibody validated in?
Anti-Ferritin Light Chain antibody (ab69090) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB) in Human, Mouse, Rat samples.

What is the molecular weight of Ferritin Light Chain?
Anti-Ferritin Light Chain (ab69090) specifically detects a band for Ferritin Light Chain (UniProt: P02792) at a molecular weight of 19kDa.

Trusted by the scientific community
Anti-Ferritin Light Chain (ab69090) was first used in a scientific publication in 2009 and has been cited over 90 times in peer-reviewed journals.

Reviewed by scientists
Anti-Ferritin Light Chain (ab69090) has over 30 independent reviews from customers.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes by the cargo receptor NCOA4 for autophagic degradation and release or iron (PubMed : 24695223).

See full target information FTL

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Publications (140)

Recent publications for all applications. Explore the full list and refine your search

Antioxidants (Basel, Switzerland) 14: PubMed40722980

2025

A High-Fat Diet Induces Oxidative Stress in OPA1 Mouse Cortices: A Critical Double Challenge.

Applications

Unspecified application

Species

Unspecified reactive species

Camille Champigny,Marlène Botella,Djamaa Atamena,Sébastien Bullich,Corentin Coustham,Bruno Guiard,Pascale Belenguer,Noélie Davezac

Cell death & disease 16:542 PubMed40691131

2025

HIF-1α alleviates ferroptosis in ulcerative colitis by regulation of GPX4.

Applications

Unspecified application

Species

Unspecified reactive species

Weitao Hu,Yanliang Cai,Daxing Cai,Zongchi Chen,Siying Huang,Su Zhang,Huie Zhuang,Taiyong Fang,Xiaoqing Chen

Scientific reports 15:21259 PubMed40596220

2025

SLC10A3 regulates ferroptosis of glioblastoma through the STAT3/GPX4 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Qian Sun,Haoran Lu,Fan'en Yuan,Qingyu Zhao,Yuxin Wei,Ronggui Wang,Qianxue Chen,Baohui Liu

BMC cardiovascular disorders 25:295 PubMed40251485

2025

Alkbh5 promotes Ythdf1 expression through demethylation thereby facilitating Fth1 translation to inhibit ferroptosis of myocardial infarction.

Applications

Unspecified application

Species

Unspecified reactive species

Mingnan Yin,Heping Liu

Brain : a journal of neurology 148:3551-3562 PubMed40070356

2025

MRI R2* captures inflammation in disconnected brain structures after stroke: a translational study.

Applications

Unspecified application

Species

Unspecified reactive species

Ismail Koubiyr,Takayuki Yamamoto,Laurent Petit,Nadège Dubourdieu,Elena Avignone,Elise Cozensa,Chloé Galmiche,Hikaru Fukutomi,Igor Sibon,Vincent Dousset,Michel Thiebaut de Schotten,Aude Panatier,Marion Tible,Thomas Tourdias

International journal of molecular sciences 26: PubMed39941155

2025

Rubiadin Mediates the Upregulation of Hepatic Hepcidin and Alleviates Iron Overload via BMP6/SMAD1/5/9-Signaling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Xueting Xie,Linyue Chang,Xinyue Zhu,Fengbei Gong,Linlin Che,Rujun Zhang,Lixin Wang,Chenyuan Gong,Cheng Fang,Chao Yao,Dan Hu,Weimin Zhao,Yufu Zhou,Shiguo Zhu

Inflammation 48:3156-3168 PubMed39920558

2025

4-octyl Itaconate Attenuates Acute Pancreatitis and Associated Lung Injury by Suppressing Ferroptosis in Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Shimin Lu,Yang Gong,Pengzhan He,Mingming Qi,Weiguo Dong

Zoological research 46:209-224 PubMed39846197

2025

Intranasal iron administration induces iron deposition, immunoactivation, and cell-specific vulnerability in the olfactory bulb of C57BL/6 mice.

Applications

Unspecified application

Species

Unspecified reactive species

Xiao-Qing Mi,Bao-Chen Liu,Le Qu,Yu Yuan,Hui Li,Ao-Yang Xu,Yu-Lin Zhang,Jun-Xia Xie,Ning Song

The Journal of biological chemistry 301:108067 PubMed39667502

2024

Iron regulatory protein 1-deficient mice exhibit hypospermatogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Aileen Harrer,Niraj Ghatpande,Tiziana Grimaldini,Daniela Fietz,Vishnu Kumar,Christiane Pleuger,Monika Fijak,Dankward T Föppl,Lennart P Rynio,Hans-Christian Schuppe,Adrian Pilatz,Marek Bartkuhn,Tara Procida-Kowalski,Noga Guttmann-Raviv,Sudhanshu Bhushan,Esther G Meyron-Holtz,Andreas Meinhardt

Frontiers in pharmacology 15:1503064 PubMed39619616

2024

Tetramethylpyrazine inhibits ferroptosis in spinal cord injury by regulating iron metabolism through the NRF2/ARE pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jingwei Tao,Jingya Zhou,Hanjie Zhu,Lin Xu,Jizhou Yang,Xiaohong Mu,Xiao Fan

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Ferritin Light Chain antibody

Western blot - Anti-Ferritin Light Chain antibody (AB69090)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

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Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (140)

Product promise