Anti-FGF1 antibody
5
(2 Reviews)
|
(15 Publications)
Rabbit Polyclonal FGF1 antibody. Suitable for ELISA, WB, sELISA, ICC/IF, IHC-Fr and reacts with Human, Rat, Recombinant full length protein - Human samples. Cited in 15 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human FGF1.
View Alternative Names
FGFA, FGF1, Fibroblast growth factor 1, FGF-1, Acidic fibroblast growth factor, Endothelial cell growth factor, Heparin-binding growth factor 1, aFGF, ECGF, HBGF-1
- sELISA
Supplier Data
Sandwich ELISA - Anti-FGF1 antibody (AB9588)
ab9588 detecting FGF-1 in sELISA
Reactivity data
Product details
Properties and storage information
Form
Reconstitution
Purification technique
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
FGF1 is involved in numerous cellular processes beyond simple cell proliferation. It binds to fibroblast growth factor receptors (FGFRs) on the cell surface initiating a cascade of downstream signaling events. This protein does not act alone; it is often a part of larger protein complexes that modulate cellular processes such as angiogenesis and wound healing. FGF1 is also implicated in nerve cell differentiation and survival through FGFR-mediated pathways.
Pathways
The FGF1 protein is integrally involved in the MAPK/ERK signaling pathway a critical pathway that regulates cell division growth and differentiation. Through this pathway FGF1 interacts with various proteins including Ras Raf and ERK to propagate the signal necessary for mitogenic and survival responses. FGF1 is also a player in the phosphoinositide 3-kinase (PI3K) pathway which helps control cellular responses to stress and metabolic regulation showing its role in cellular homeostasis.
Product protocols
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Target data
Publications (15)
Recent publications for all applications. Explore the full list and refine your search
Nature communications 15:9667 PubMed39516487
2024
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Cells 11: PubMed35954241
2022
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Hepatology communications 6:1574-1588 PubMed35271760
2022
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Anatomia, histologia, embryologia 50:645-657 PubMed33772852
2021
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Medical science monitor : international medical jo 26:e924394 PubMed33020467
2020
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QJM : monthly journal of the Association of Physicians 113:859-869 PubMed32176291
2020
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Clinical cancer research : an official journal of 25:7202-7217 PubMed31515463
2019
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Journal of cellular biochemistry 120:19087-19097 PubMed31264280
2019
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Journal of cellular and molecular medicine 23:4422-4433 PubMed30993882
2019
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International journal of cancer 144:322-333 PubMed30110127
2018
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Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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