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AB198201

Anti-FGF3 antibody

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(1 Publication)

Rabbit Polyclonal FGF3 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human FGF3.

View Alternative Names

INT2, FGF3, Fibroblast growth factor 3, FGF-3, Heparin-binding growth factor 3, Proto-oncogene Int-2, HBGF-3

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FGF3 antibody (AB198201)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FGF3 antibody (AB198201)

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling FGF3 with ab198201 at a 1/20 dilution.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human FGF3. The exact immunogen used to generate this antibody is proprietary information.

P11487

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Complementary Products

Assay Kits

AB313606

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Primary Antibodies

AB203589

Anti-Wnt8a antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Wnt8a antibody (AB203589)

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Primary Antibodies

AB154640

Anti-ZNF83 antibody - N-terminal

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Assay Kits

AB313606

Human FGF3 ELISA Kit

Sandwich ELISA - Human FGF3 ELISA Kit (AB313606)

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/25 - 1/100", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FGF3 also known as fibroblast growth factor 3 is a protein involved in important cellular processes like cell proliferation and differentiation. The protein has a mass of approximately 30 kDa. It is mainly expressed in the developing brain inner ear and other embryonic structures. FGF3 belongs to the fibroblast growth factor family which consists of several proteins known for their role in various biological activities. The family's versatility makes FGF3's function significant during embryogenesis.
Biological function summary

Fibroblast growth factor 3 plays an important role in the regulation of embryonic development and morphogenesis. The protein acts as a ligand that binds to fibroblast growth factor receptors (FGFRs) triggering cascades responsible for cellular growth. Although FGF3 does not form complexes it often works in coordination with other growth factors to facilitate developmental pathways through receptor-mediated signaling. Its involvement is important to the development of the central nervous system and auditory structures.

Pathways

Fibroblast growth factor 3 takes part in the FGFR signaling pathway which is essential for multiple developmental processes. This pathway interacts closely with other signaling systems like the MAPK/ERK pathway that influence cell division and differentiation. FGF3 shares a connection with other members of the FGF family such as FGF8 in regulating these pathways. Interactions with FGFRs and downstream MAPK signal transduction highlight its importance in development and cellular function.

Disruptions in fibroblast growth factor 3 activity have been associated with conditions such as LAMM syndrome and otodental dysplasia. LAMM syndrome involves hearing loss and abnormalities in the inner ear highlighting FGF3's role in auditory development. The protein's interaction with FGFR2 mutations has been linked to such syndromes indicating a complex relationship in disease phenotypes. The association of FGF3 with specific developmental disorders reflects its critical contributions to normal cellular and tissue development.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal ear development.
See full target information FGF3
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Brain and behavior 15:e70377 PubMed40320842

2025

Analysis and Identification of Therapeutic Targets for Neuronal Regeneration After Ischemic Stroke.

Applications

Unspecified application

Species

Unspecified reactive species

Xiao-Li Min,Li Guo,Zhenyu Wang,Lei Zhao,Chenglong Shi,Xiaoyong Liu,Zhen Wang,Fei-Fei Shang,Jiaping Wang
View all publications
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Product promise

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