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AB194793

Anti-FIBP antibody

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(1 Publication)

Rabbit Polyclonal FIBP antibody. Suitable for WB and reacts with Human, Rat samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human FIBP.

View Alternative Names

Acidic fibroblast growth factor intracellular-binding protein, aFGF intracellular-binding protein, FGF-1 intracellular-binding protein, FIBP

1 Images
Western blot - Anti-FIBP antibody (AB194793)
  • WB

Supplier Data

Western blot - Anti-FIBP antibody (AB194793)

All lanes:

Western blot - Anti-FIBP antibody (ab194793) at 1/500 dilution

Lane 1:

SW620 cell extract

Lane 2:

MCF-7 cell extract

Lane 3:

Rat brain cell extract

Predicted band size: 42 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rat, Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human FIBP.

O43427

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FIBP also known as FGF-binding protein is a protein with a molecular mass of approximately 42 kDa. This protein interacts mechanically with fibroblast growth factors (FGFs) and affects their activity. FIBP is expressed in various tissues including brain heart and kidney. Researchers have studied how it binds to acidic and basic FGFs which play roles in multiple cellular processes.
Biological function summary

FIBP influences the modulation of cell growth and differentiation. It does not form a known complex but interacts with FGFs impacting their bioavailability and function. These roles make it integral to cellular processes where FGF signaling is important such as tissue repair and embryonic development. Understanding its interaction with FGFs helps in studying various physiological and pathological states.

Pathways

FIBP plays a role in the fibroblast growth factor signaling pathway. This pathway involves FGFRs (fibroblast growth factor receptors) and proteins such as ERK1/2 which are essential for signal transduction. FIBP affects FGF localization and modulation influencing how signals propagate within the pathway. This regulation holds importance in cellular proliferation and survival key functions within the growth factor signaling networks.

FIBP has associations with cancer and developmental disorders. Abnormal FGF signaling mediated by FIBP can lead to tumorigenesis and aberrant development. FGF interactions connect FIBP with FGFR mutations or dysregulations often seen in various cancers. Understanding the relationship between FIBP and disease pathways advances research on therapeutic targets and diagnostic markers.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in mitogenic function of FGF1. May mediate with IER2 FGF-signaling in the establishment of laterality in the embryo (By similarity).
See full target information FIBP
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

iScience 28:112266 PubMed40241752

2025

CRISPR/Cas9-mediated SHP-1-knockout T cells combined with simvastatin enhances anti-tumor activity in humanized-PDX HCC model.

Applications

Unspecified application

Species

Unspecified reactive species

Huaping Liu,Wu Ge,Xiaoping Yu,Jianwei Luo,Juan Zhang,Min Yang,Lu Cao,Yangnan Zhang,Ruike Wang,Cejun Yang,Pei Li,Mengyu Tian,XiaoPei Peng,Lei Peng,Di Wu,Muqi Liu,Qi Liang,Shengwang Zhang,Wei Li,Pengfei Rong,Hailan Li,Xiaoqian Ma,Wei Wang
View all publications
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Product promise

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