AB118488

Anti-Fibrinogen antibody

Name: Anti-Fibrinogen antibody (ab118488) | Abcam
Brand: Abcam Limited
SKU: AB118488
Price: 605 USD
Availability: InStock

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(4 Publications)

Goat Polyclonal Fibrinogen alpha chain antibody. Suitable for IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human FGA.

View Alternative Names

Fibrinogen alpha chain, FGA

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Fibrinogen antibody (AB118488)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Fibrinogen antibody (AB118488)

ab118488 at 2.5μg/ml staining Fibrinogen in Formalin-fixed, Paraffin-embedded Human kidney tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Fibrinogen antibody (AB118488)

ab118488 at 2.5μg/ml staining Fibrinogen in Formalin-fixed, Paraffin-embedded Human liver tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human FGA. The exact immunogen used to generate this antibody is proprietary information.

P02671

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "2.5 µg/mL", "IHCP-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purity

IgG fraction

Storage buffer

pH: 7.2 Preservative: 0.01% Sodium azide Constituents: 0.88% Sodium chloride, 0.424% Tripotassium orthophosphate

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

See full target information FGA

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Journal of biomedical materials research. Part B, Applied biomaterials 110:527-534 PubMed34492134

2021

Enhancement of the anticoagulant capacity of polyvinyl chloride tubing for cardiopulmonary bypass circuit using aluminum oxide nanoscale coating applied through atomic layer deposition.

Applications

Unspecified application

Species

Unspecified reactive species

Chen-Chie Wang,Li-Chun Wang,Kai-Chiang Yang,Miin-Jang Chen,Hsin-Chih Lin,Yin-Yi Han

Biomaterials 273:120827 PubMed33910079

2021

PEGylated nanoparticle albumin-bound steroidal ginsenoside derivatives ameliorate SARS-CoV-2-mediated hyper-inflammatory responses.

Applications

Unspecified application

Species

Unspecified reactive species

Hee Ho Park,Hyelim Kim,Han Sol Lee,Eun U Seo,Ji-Eun Kim,Jee-Hyun Lee,Yong-Hyeon Mun,So-Yeol Yoo,Jiseon An,Mi-Young Yun,Nae-Won Kang,Dae-Duk Kim,Dong Hee Na,Kyung Soo Hong,Jong Geol Jang,June Hong Ahn,Jong-Sup Bae,Gyu Yong Song,Jae-Young Lee,Hong Nam Kim,Wonhwa Lee

American journal of physiology. Renal physiology 315:F1283-F1294 PubMed29923769

2018

Intrarenal Toll-like receptor 4 and Toll-like receptor 2 expression correlates with injury in antineutrophil cytoplasmic antibody-associated vasculitis.

Applications

Unspecified application

Species

Unspecified reactive species

Kim M O'Sullivan,Sharon L Ford,Anthony Longano,A Richard Kitching,Stephen R Holdsworth

EBioMedicine 32:215-222 PubMed29779699

2018

Recellularization of Decellularized Venous Grafts Using Peripheral Blood: A Critical Evaluation.

Applications

IHC-Fr

Species

Human

Mia H Rambøl,Jonny Hisdal,Jon O Sundhagen,Jan E Brinchmann,Antonio Rosales

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Fibrinogen antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Fibrinogen antibody (AB118488)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Fibrinogen antibody (AB118488)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Product protocols

Target data

Publications (4)

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