AB244636

Anti-Fibrinogen antibody [EPR19765-189] - BSA and Azide free (Capture)

RabMAb
Recombinant
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Anti-Fibrinogen antibody [EPR19765-189] - BSA and Azide free (Capture) (ab244636) is a rabbit recombinant monoclonal antibody provided in a PBS only buffer for easy conjugation detecting Fibrinogen alpha (FGA) in ELISA. Suitable for Human.

- BSA, sodium azide, and glycerol-free for easy conjugation
- Biophysical QC for unrivalled batch-batch consistency

View Alternative Names

Fibrinogen alpha chain, FGA

1 Images

Sandwich ELISA - Anti-Fibrinogen antibody [EPR19765-189] - BSA and Azide free (Capture) (AB244636)

sELISA

Supplier Data

Sandwich ELISA - Anti-Fibrinogen antibody [EPR19765-189] - BSA and Azide free (Capture) (AB244636)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab241383).

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR19765-189

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

This antibody does not cross-react with Human Fibrinogen alpha, Human Fibrinogen beta, and Human Fibrinogen gamma.

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Reactivity data

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Product details

Product Specifications
Anti-Fibrinogen antibody [EPR19765-189] - BSA and Azide free (Capture) (ab244636) is a recombinant rabbit monoclonal antibody which was developed by Abcam using patented rabbit monoclonal antibody technology.
ab244636 is provided in a carrier-free, conjugation ready format, and is validated in sELISAin human samples.
Carrier-free antibodies are compatible with our best-in-class range of Lightning-Link® conjugation kits.
Anti-Fibrinogen antibody [EPR19765-189] - BSA and Azide free (Capture) (ab244636) specifically detects Fibrinogen (UniProt ID: P02671; Molecular weight: 91kDa) and is sold in 100 ug and 1mg selling sizes.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

Constituents: 100% PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

See full target information FGA

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Fibrinogen antibody [EPR19765-189] - BSA and Azide free (Capture)

Sandwich ELISA - Anti-Fibrinogen antibody [EPR19765-189] - BSA and Azide free (Capture) (AB244636)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Complementary Products

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Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise