AB137728

Anti-Fibrinogen gamma chain antibody

Name: Anti-Fibrinogen gamma chain antibody (ab137728) | Abcam
Brand: Abcam Limited
SKU: AB137728
Price: 535 USD
Availability: InStock

Be the first to review this product! Submit a review

(2 Publications)

Rabbit Polyclonal Fibrinogen gamma chain antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FGG aa 150-400.

View Alternative Names

PRO2061, FGG, Fibrinogen gamma chain

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-Fibrinogen gamma chain antibody (AB137728)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Fibrinogen gamma chain antibody (AB137728)

Immunofluorescent analysis of paraformaldehyde-fixed HeLa cells labelling Fibrinogen gamma chain with ab137728 at 1/200 dilution. Lower image is co-stained with Hoechst 33342.

Supplier Data

Western blot - Anti-Fibrinogen gamma chain antibody (AB137728)

Samples were separated by 10% SDS-PAGE.

All lanes:

Western blot - Anti-Fibrinogen gamma chain antibody (ab137728) at 1/2000 dilution

All lanes:

Human plasma at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 52 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human FGG aa 150-400. The exact immunogen used to generate this antibody is proprietary information.

P02679

style

left-column

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

See full target information FGG

style

left-column

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Blood 138:1359-1372 PubMed34375384

2021

An alternate covalent form of platelet αIIbβ3 integrin that resides in focal adhesions and has altered function.

Applications

Unspecified application

Species

Unspecified reactive species

Aster E Pijning,Mitchell T Blyth,Michelle L Coote,Freda Passam,Joyce Chiu,Philip J Hogg

Blood advances 4:2939-2949 PubMed32603423

2020

Dominant role of αIIbβ3 in platelet interactions with cross-linked fibrin fragment D-dimer.

Applications

Unspecified application

Species

Unspecified reactive species

Lorena Buitrago,Hina Zafar,Yixiao Zhang,Jihong Li,Thomas Walz,Barry S Coller

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Fibrinogen gamma chain antibody

Immunocytochemistry/ Immunofluorescence - Anti-Fibrinogen gamma chain antibody (AB137728)

Western blot - Anti-Fibrinogen gamma chain antibody (AB137728)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Alternative Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Complementary Products

Assay Kits

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (2)

Product promise