Rabbit Recombinant Monoclonal Fibrinogen gamma chain antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.
Images
![Western blot - Anti-Fibrinogen gamma chain antibody [EPR3085] (AB133339), expandable thumbnail](https://content.abcam.com/products/images/fibrinogen-gamma-chain-antibody-epr3085-ab133339--western-blot-img31268.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Fibrinogen gamma chain antibody [EPR3085] (AB133339)")
Publications
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- Molecular neurobiology 54:888-8942016Gastrin-Releasing Peptide Receptor Knockdown Induces Senescence in Glioblastoma Cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPâmela Rossi Menegotto,Patrícia Luciana da Costa Lopez,Bárbara Kunzler Souza,Caroline Brunetto de Farias,Eduardo Cremonese Filippi-Chiela,Igor Araújo Vieira,Gilberto Schwartsmann,Guido Lenz,Rafael RoeslerPubMed 26780458
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 0.1% BSA- Form
Liquid
- Clonality
Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| IP | WB | IHC-P | ICC/IF | |
|---|---|---|---|---|
| Human | Not recommended | Tested | Not recommended | Not recommended |
IP
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/1000 - 1/10000 | Notes - |
IHC-P
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
ICC/IF
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
Associated Products
Select an associated product type
5 products for Alternative Product
Target data
Function
Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Alternative names
Fibrinogen gamma chain, FGG, PRO2061
Recommended products
Rabbit Recombinant Monoclonal Fibrinogen gamma chain antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 0.1% BSA- Form
Liquid
- Clonality
Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
EPR3085
- Purity
Tissue culture supernatant
- Concentration
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Storage information
Stable for 12 months at -20°C
Notes
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
![Western blot - Anti-Fibrinogen gamma chain antibody [EPR3085] (ab133339), expandable thumbnail](https://content.abcam.com/products/images/fibrinogen-gamma-chain-antibody-epr3085-ab133339--western-blot-img31268.jpg "Western blot - Anti-Fibrinogen gamma chain antibody [EPR3085] (ab133339)")
Western blot - Anti-Fibrinogen gamma chain antibody [EPR3085] (ab133339)
All lanes: Western blot - Anti-Fibrinogen gamma chain antibody [EPR3085] (ab133339) at 1/1000 dilution
All lanes: Human plasma cell lysate at 10 µg
SecondaryAll lanes: Goat Anti-rabbit HRP at 1/2000 dilution
Predicted band size: 52 kDa
Downloads
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