Rabbit Recombinant Monoclonal Fibulin 1 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.
Images
![Western blot - Anti-Fibulin 1 antibody [EPR10913] (AB175204), expandable thumbnail](https://content.abcam.com/products/images/fibulin-1-antibody-epr10913-ab175204--western-blot-img150425.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Fibulin 1 antibody [EPR10913] (AB175204)")
Publications
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- Neural regeneration research 18:587-5932022Proteomics of serum exosomes identified fibulin-1 as a novel biomarker for mild cognitive impairment.Applications:Unspecified applicationReactive species:Unspecified reactive speciesBo Chen,Li Song,Juan Yang,Wei-Ying Zhou,Yuan-Yuan Cheng,Yu-Jie LaiPubMed 36018182
- Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 27:242-2482021FBLN1 promotes chondrocyte proliferation by increasing phosphorylation of Smad2.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGang Xu,Xiang Geng,Fan Yang,Haijiao ZhangPubMed 33610427
- JCI insight 5:2019Fibulin-1c regulates transforming growth factor-β activation in pulmonary tissue fibrosis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGang Liu et. al.PubMed 31343988
- The Prostate 77:729-7422017Identification of Fibulin-1 as a Human Bone Marrow Stromal (HS-5) Cell-Derived Factor That Induces Human Prostate Cancer Cell Death.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKornkamon Lertsuwan,Leila H Choe,Irene R Marwa,Kelvin Lee,Robert A SikesPubMed 28168724
- JCI insight 1:2016Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGang Liu,Marion A Cooley,Andrew G Jarnicki,Alan C-Y Hsu,Prema M Nair,Tatt Jhong Haw,Michael Fricker,Shaan L Gellatly,Richard Y Kim,Mark D Inman,Gavin Tjin,Peter A B Wark,Marjorie M Walker,Jay C Horvat,Brian G Oliver,W Scott Argraves,Darryl A Knight,Janette K Burgess,Philip M HansbroPubMed 27398409
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
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Reactivity data
Select an application| WB | IHC-P | ICC/IF | |
|---|---|---|---|
| Human | Tested | Not recommended | Not recommended |
| Mouse | Predicted | Not recommended | Not recommended |
| Rat | Predicted | Not recommended | Not recommended |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/1000 - 1/5000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat | Dilution info - | Notes - |
IHC-P
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human, Mouse, Rat | Dilution info - | Notes - |
ICC/IF
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human, Mouse, Rat | Dilution info - | Notes - |
Associated Products
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2 products for Alternative Product
Target data
Function
Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.
Alternative names
PP213, FBLN1, Fibulin-1, FIBL-1
Recommended products
Rabbit Recombinant Monoclonal Fibulin 1 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
- EPR10913
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
![Western blot - Anti-Fibulin 1 antibody [EPR10913] (ab175204), expandable thumbnail](https://content.abcam.com/products/images/fibulin-1-antibody-epr10913-ab175204--western-blot-img150425.jpg "Western blot - Anti-Fibulin 1 antibody [EPR10913] (ab175204)")
Western blot - Anti-Fibulin 1 antibody [EPR10913] (ab175204)
All lanes: Western blot - Anti-Fibulin 1 antibody [EPR10913] (ab175204) at 1/1000 dilution
Lane 1: Human placenta tissue lysate at 1/10 dilution
Lane 2: Fetal liver tissue lysate at 1/10 dilution
Lane 3: Fetal heart tissue lysate at 1/10 dilution
Predicted band size: 77 kDa
Observed band size: 95 kDa
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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