AB175204

Anti-Fibulin 1 antibody [EPR10913]

RabMAb
Recombinant
What is this?

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(6 Publications)

Rabbit Recombinant Monoclonal Fibulin 1 antibody. Suitable for WB and reacts with Human samples. Cited in 6 publications.

View Alternative Names

PP213, FBLN1, Fibulin-1, FIBL-1

1 Images

Supplier Data

Western blot - Anti-Fibulin 1 antibody [EPR10913] (AB175204)

All lanes:

Western blot - Anti-Fibulin 1 antibody [EPR10913] (ab175204) at 1/1000 dilution

Lane 1:

Human placenta tissue lysate at 1/10 dilution

Lane 2:

Fetal liver tissue lysate at 1/10 dilution

Lane 3:

Fetal heart tissue lysate at 1/10 dilution

Predicted band size: 77 kDa

Observed band size: 95 kDa

false

Carrier free

Anti-Fibulin 1 antibody [EPR10913] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR10913

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.

See full target information FBLN1

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Cellular and molecular life sciences : CMLS 82:192 PubMed40323446

2025

Fibulin-1 deficiency alleviates liver fibrosis by inhibiting hepatic stellate cell activation via the p38 MAPK pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Wenshan Zhao,Jingyu Zhang,Qingdong Guo,Qi Wang,Hong Zhao,Fan Xiao,Ming Han,Ying Cao,Rui Ding,Aiting Yang,Wen Xie

Neural regeneration research 18:587-593 PubMed36018182

2022

Proteomics of serum exosomes identified fibulin-1 as a novel biomarker for mild cognitive impairment.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Chen,Li Song,Juan Yang,Wei-Ying Zhou,Yuan-Yuan Cheng,Yu-Jie Lai

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 27:242-248 PubMed33610427

2021

FBLN1 promotes chondrocyte proliferation by increasing phosphorylation of Smad2.

Applications

Unspecified application

Species

Unspecified reactive species

Gang Xu,Xiang Geng,Fan Yang,Haijiao Zhang

JCI insight 5: PubMed31343988

2019

Fibulin-1c regulates transforming growth factor-β activation in pulmonary tissue fibrosis.

Applications

Unspecified application

Species

Unspecified reactive species

Gang Liu,Marion A Cooley,Andrew G Jarnicki,Theo Borghuis,Prema M Nair,Gavin Tjin,Alan C Hsu,Tatt Jhong Haw,Michael Fricker,Celeste L Harrison,Bernadette Jones,Nicole G Hansbro,Peter A Wark,Jay C Horvat,W Scott Argraves,Brian G Oliver,Darryl A Knight,Janette K Burgess,Philip M Hansbro

The Prostate 77:729-742 PubMed28168724

2017

Identification of Fibulin-1 as a Human Bone Marrow Stromal (HS-5) Cell-Derived Factor That Induces Human Prostate Cancer Cell Death.

Applications

Unspecified application

Species

Unspecified reactive species

Kornkamon Lertsuwan,Leila H Choe,Irene R Marwa,Kelvin Lee,Robert A Sikes

JCI insight 1: PubMed27398409

2016

Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases.

Applications

Unspecified application

Species

Unspecified reactive species

Gang Liu,Marion A Cooley,Andrew G Jarnicki,Alan C-Y Hsu,Prema M Nair,Tatt Jhong Haw,Michael Fricker,Shaan L Gellatly,Richard Y Kim,Mark D Inman,Gavin Tjin,Peter A B Wark,Marjorie M Walker,Jay C Horvat,Brian G Oliver,W Scott Argraves,Darryl A Knight,Janette K Burgess,Philip M Hansbro

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Fibulin 1 antibody [EPR10913]

Western blot - Anti-Fibulin 1 antibody [EPR10913] (AB175204)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (6)

Product promise