Mouse Monoclonal Filaggrin antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FLG aa 950-1150.
Images
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Filaggrin antibody [FLG/1562] (AB218397), expandable thumbnail](https://content.abcam.com/products/images/filaggrin-antibody-flg-1562-ab218397--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img3613.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Filaggrin antibody [FLG/1562] (AB218397)")
Publications
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- The Journal of investigative dermatology 142:1499-1502.e42021RACK1 Prevents the Premature Differentiation of Epidermal Progenitor Cells by Inhibiting IRF6 Expression.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJi Ling,Manisha Tiwari,Yifang Chen,George L SenPubMed 34742704
- Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 18:1727-1735.e22019Impedance and Histologic Characteristics of the Sub-Laryngeal Esophagus Distinguish Eosinophilic Esophagitis From Other Esophageal Disorders.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYash A Choksi,Jasmine Chaparro,Michael Blanco,Rohit Sharda,Shabnam Sarker,Sarah Ferguson,Tina Higginbotham,Girish Hiremath,Frank Revetta,M Kay Washington,Christopher S Williams,Michael F VaeziPubMed 31589979
Key facts
- Isotype
- IgG1
- Host species
- Mouse
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Recombinant Fragment Protein within Human FLG aa 950-1150. The exact immunogen used to generate this antibody is proprietary information. Database link P20930
Reactivity data
Select an application| IHC-P | |
|---|---|
| Human | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 0.5-1 µg/mL | Notes (Primary incubation for 30 minutes at RT). Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Associated Products
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1 product for Alternative Version
7 products for Alternative Product
Target data
Function
Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.
Alternative names
Filaggrin, FLG
Recommended products
Mouse Monoclonal Filaggrin antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FLG aa 950-1150.
Key facts
- Isotype
- IgG1
- Host species
- Mouse
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Recombinant Fragment Protein within Human FLG aa 950-1150. The exact immunogen used to generate this antibody is proprietary information. Database link P20930
- Clone number
- FLG/1562
- Purification technique
- Affinity purification Protein G
- Light chain type
- kappa
- Concentration
- Purification notes
ab218397 was purified from Bioreactor Concentrate by Protein A/G.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Filaggrin antibody [FLG/1562] (ab218397), expandable thumbnail](https://content.abcam.com/products/images/filaggrin-antibody-flg-1562-ab218397--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img3613.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Filaggrin antibody [FLG/1562] (ab218397)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Filaggrin antibody [FLG/1562] (ab218397)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human skin tissue labeling Filaggrin with ab218397 at 1 μg/ml.
Downloads
Product protocols
- Visit the general protocols
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