AB234406

Anti-Filaggrin antibody [FLG/1957R]

Recombinant
What is this?

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(5 Publications)

Rabbit Recombinant Monoclonal Filaggrin antibody. Suitable for IHC-P and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FLG aa 150-300.

View Alternative Names

Filaggrin, FLG

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Filaggrin antibody [FLG/1957R] (AB234406)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Filaggrin antibody [FLG/1957R] (AB234406)

Formalin-fixed, paraffin-embedded human skin tissue stained for Filaggrin using ab234406 at 1 μg/ml in immunohistochemical analysis.

Carrier free

Anti-Filaggrin antibody [FLG/1957R] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

FLG/1957R

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human FLG aa 150-300. The exact immunogen used to generate this antibody is proprietary information.

P20930

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "0.5-1 µg/mL", "IHCP-species-notes": "<p>Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Incubate with primary antibody for 30 minutes at room temperature.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification

Purification notes

Purified from bioreactor concentrate by Protein A/G.

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.

See full target information FLG

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Biomedicines 12: PubMed39335502

2024

Inflammaging: Expansion of Molecular Phenotype and Role in Age-Associated Female Infertility.

Applications

Unspecified application

Species

Unspecified reactive species

Dmitry Ivanov,Anna Drobintseva,Valeriia Rodichkina,Ekaterina Mironova,Tatyana Zubareva,Yuliya Krylova,Svetlana Morozkina,Maria Greta Pia Marasco,Gianluigi Mazzoccoli,Ruslan Nasyrov,Igor Kvetnoy

Mucosal immunology 16:567-577 PubMed37302713

2023

Mast cells disrupt the function of the esophageal epithelial barrier.

Applications

Unspecified application

Species

Unspecified reactive species

Mirelle T A Kleuskens,Marie K Bek,Youmna Al Halabi,Bart R J Blokhuis,Mara A P Diks,Maria L Haasnoot,Johan Garssen,Albert J Bredenoord,Betty C A M van Esch,Frank A Redegeld

The Journal of dermatology 50:999-1007 PubMed37157942

2023

Barrier function and ultrastructure characteristics of epidermis in patients with primary cutaneous amyloidosis.

Applications

Unspecified application

Species

Unspecified reactive species

Yuling Zhang,Ya Le,Junyi Guo,Fangfang Wu,Qing Li,Ping Lu

ImmunoHorizons 5:830-843 PubMed34702760

2021

Transcriptomic Analysis of Healthy and Atopic Dermatitis Samples Reveals the Role of IL-37 in Human Skin.

Applications

Unspecified application

Species

Unspecified reactive species

Jiajun Zhou,David C Gemperline,Matthew J Turner,Jonathan Oldach,Jennifer Molignano,Jonathan T Sims,Keith R Stayrook

Allergy 77:1510-1521 PubMed34458999

2021

Butyrate and propionate restore interleukin 13-compromised esophageal epithelial barrier function.

Applications

Unspecified application

Species

Unspecified reactive species

Mirelle T A Kleuskens,Maria L Haasnoot,Bart M Herpers,Marleen T J van Ampting,Albert J Bredenoord,Johan Garssen,Frank A Redegeld,Betty C A M van Esch

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Filaggrin antibody [FLG/1957R]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Filaggrin antibody [FLG/1957R] (AB234406)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (5)

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