AB218863

Anti-Filaggrin antibody [SPM181] - BSA and Azide free

Name: Anti-Filaggrin antibody [SPM181] - BSA and Azide free (ab218863) | Abcam
Brand: Abcam Limited
SKU: AB218863
Price: 905 USD
Availability: InStock
Rating: 5 (1 reviews)

(1 Review)

(4 Publications)

Mouse Monoclonal Filaggrin antibody. Carrier free. Suitable for IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human FLG.

View Alternative Names

Filaggrin, FLG

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

SPM181

Isotype

IgG1

Light chain type

kappa

Carrier free

Yes

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Full Length Protein corresponding to Human FLG.

P20930

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "0.5-1 µg/mL", "IHCP-species-notes": "<p>(Primary incubation for 30 min at RT).</p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Purification notes

ab218863 was purified from Bioreactor Concentrate by Protein A/G.

Storage buffer

pH: 7.2 - 7.4 Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.

See full target information FLG

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Experimental dermatology 32:2160-2165 PubMed36995036

2023

Altered expression of S100 fused-type proteins in an atopic dermatitis skin model.

Applications

Unspecified application

Species

Unspecified reactive species

Teruhiko Makino,Megumi Mizawa,Keita Takemoto,Seiji Yamamoto,Tadamichi Shimizu

Cell death discovery 6:109 PubMed33133644

2020

Trichohyalin-like 1 protein plays a crucial role in proliferation and anti-apoptosis of normal human keratinocytes and squamous cell carcinoma cells.

Applications

Unspecified application

Species

Unspecified reactive species

Teruhiko Makino,Megumi Mizawa,Yoko Yoshihisa,Seiji Yamamoto,Yoshiaki Tabuchi,Masashi Miyai,Toshihiko Hibino,Masakiyo Sasahara,Tadamichi Shimizu

The Journal of investigative dermatology 140:1938-1950.e5 PubMed32199994

2020

Rosacea Is Characterized by a Profoundly Diminished Skin Barrier.

Applications

Unspecified application

Species

Unspecified reactive species

Barbara Medgyesi,Zsolt Dajnoki,Gabriella Béke,Krisztián Gáspár,Imre Lőrinc Szabó,Eszter Anna Janka,Szilárd Póliska,Zoltán Hendrik,Gábor Méhes,Dániel Törőcsik,Tamás Bíró,Anikó Kapitány,Andrea Szegedi

The Journal of allergy and clinical immunology 135:1659-61.e4 PubMed25863977

2015

IL-33 impacts on the skin barrier by downregulating the expression of filaggrin.

Applications

Unspecified application

Species

Unspecified reactive species

Jenny Seltmann,Lennart M Roesner,Friedrich-Wilhelm von Hesler,Miriam Wittmann,Thomas Werfel

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Filaggrin antibody [SPM181] - BSA and Azide free

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (4)

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