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Mouse Monoclonal CD14 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human samples. Cited in 10 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human CD14.
Alternative names=Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14
- Isotype
IgG1
- Host species
Mouse
- Conjugation
FITC
- Excitation/Emission
Ex: 495nm, Em: 519nm
- Storage buffer
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 0.2% BSA- Form
Liquid
- Clonality
Monoclonal
- Immunogen
Native Full Length Protein corresponding to Human CD14. Database link: P08571
Reactivity data
Select an application| Flow Cyt | |
|---|---|
| Human | Tested |
Images
Flow Cyt
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 20 µL for 106 Cells | Notes or 100 μl of whole blood. |
Target data
Function
Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655, PubMed:22265692). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-) (PubMed:23880187).
Recommended products
Mouse Monoclonal CD14 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human samples. Cited in 10 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human CD14.
Alternative names=Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14
Key facts
- Isotype
IgG1
- Host species
Mouse
- Conjugation
FITC
- Excitation/Emission
Ex: 495nm, Em: 519nm
- Storage buffer
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 0.2% BSA- Form
Liquid
- Clonality
Monoclonal
- Immunogen
Native Full Length Protein corresponding to Human CD14. Database link: P08571
- Clone number
MEM-15
- Purification technique
Affinity purification Protein A
- Specificity
Ab28061 recognises CD14 expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. Ab28061 also recognises soluble forms of CD14 found in serum and in the urine of some nephrotic patients.
- Concentration
Storage
- Shipped at conditions
Blue Ice
- Appropriate long-term storage conditions
+4°C
Notes
The antibody is free of unconjugated FITC.
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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