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AB27333

FITC Anti-CD31 antibody [B-B38]

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(7 Publications)

Mouse Monoclonal CD31 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human samples. Cited in 7 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PECAM1.

View Alternative Names

CD31, Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, PECAM1

1 Images
Flow Cytometry - FITC Anti-CD31 antibody [B-B38] (AB27333)
  • Flow Cyt

Unknown

Flow Cytometry - FITC Anti-CD31 antibody [B-B38] (AB27333)

Flow cytometry analysis staining CD31 in human platelet cells using ab27333.

This image was generated using the ascites version of the product.

  • Carrier free

    Anti-CD31 antibody [B-B38] - BSA and Azide free

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

B-B38

Isotype

IgG1

Light chain type

kappa

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Recombinant Full Length Protein corresponding to Human PECAM1.

P16284

Specificity

This antibody is specific for CD31.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "10 µL for 10^6 Cells", "FlowCyt-species-notes": "<p>Use 10 μl to label 10<sup>6</sup> cells or 100 μl of whole blood.</p><p><a href='/en-us/products/primary-antibodies/fitc-mouse-igg1-b11-6-isotype-control-ab91356'>ab91356</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }
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Product details

This product was changed from ascites to tissue culture supernatant on 19th June 2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
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Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Purification notes
Conjugated from an Affinity purified culture supernatant.
Storage buffer
pH: 7.3 - 7.5 Preservative: 0.1% Sodium azide Constituents: PBS, 5% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed : 17580308, PubMed : 19342684). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed : 19342684). Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions (PubMed : 27958302). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed : 17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed : 12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed : 12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed : 18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed : 18672896). Induces susceptibility to atherosclerosis (By similarity).. Isoform Delta15. Does not protect against apoptosis.
See full target information PECAM1
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Publications (7)

Recent publications for all applications. Explore the full list and refine your search

Regenerative therapy 25:35-48 PubMed38058606

2023

Epigenetic mechanism of miR-26b-5p-enriched MSCs-EVs attenuates spinal cord injury.

Applications

Unspecified application

Species

Unspecified reactive species

Jinghui Xu,Zhenxiao Ren,Tianzuo Niu,Siyuan Li

PloS one 15:e0228510 PubMed32407317

2020

Neurons from human mesenchymal stem cells display both spontaneous and stimuli responsive activity.

Applications

Unspecified application

Species

Unspecified reactive species

Nihal Karakaş,Sadık Bay,Nezaket Türkel,Nurşah Öztunç,Merve Öncül,Hülya Bilgen,Khalid Shah,Fikrettin Şahin,Gürkan Öztürk

Arteriosclerosis, thrombosis, and vascular biology 39:413-431 PubMed30700131

2019

Potential Role of H-Ferritin in Mitigating Valvular Mineralization.

Applications

Unspecified application

Species

Unspecified reactive species

Katalin Éva Sikura,László Potor,Tamás Szerafin,Abolfazl Zarjou,Anupam Agarwal,Paolo Arosio,Maura Poli,Zoltán Hendrik,Gábor Méhes,Melinda Oros,Niké Posta,Lívia Beke,Ibolya Fürtös,György Balla,József Balla

Arteriosclerosis, thrombosis, and vascular biology 39:482-495 PubMed30626206

2019

Spermine on Endothelial Extracellular Vesicles Mediates Smoking-Induced Pulmonary Hypertension Partially Through Calcium-Sensing Receptor.

Applications

Unspecified application

Species

Unspecified reactive species

Liping Zhu,Rui Xiao,Xiuyun Zhang,Yuheng Lang,Fangbo Liu,Zhe Yu,Jiwei Zhang,Yuan Su,Yankai Lu,Tao Wang,Shengquan Luo,Jian Wang,Ming-Lin Liu,Jocelyn Dupuis,Zhi-Cheng Jing,Tong Li,Weining Xiong,Qinghua Hu

mBio 7: PubMed27406562

2016

Interaction between Endothelial Protein C Receptor and Intercellular Adhesion Molecule 1 to Mediate Binding of Plasmodium falciparum-Infected Erythrocytes to Endothelial Cells.

Applications

Flow Cyt

Species

Human

Marion Avril,Maria Bernabeu,Maxwell Benjamin,Andrew Jay Brazier,Joseph D Smith

International journal of clinical and experimental 7:2861-70 PubMed25031705

2014

PDGFR-β (+) perivascular cells from infantile hemangioma display the features of mesenchymal stem cells and show stronger adipogenic potential in vitro and in vivo.

Applications

Flow Cyt

Species

Human

Si-Ming Yuan,Yao Guo,Xiao-Jun Zhou,Wei-Min Shen,Hai-Ni Chen

Proceedings of the National Academy of Sciences of the United States of America 98:1805-10 PubMed11172032

2001

Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria.

Applications

Unspecified application

Species

Unspecified reactive species

A Pain,D J Ferguson,O Kai,B C Urban,B Lowe,K Marsh,D J Roberts
View all publications
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Product promise

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