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BiochemicalsProteins and Peptides
Proteins and peptidesAnti-Ly6g antibody [1A8] - mouse IgG2c (Chimeric)
Low endotoxin, Azide free.
Our first-to-market chimera with mouse IgG2c backbone, this functional antibody specifically depletes neutrophils in vivo for up to 72h.
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Mouse Monoclonal CD31 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Rat samples. Cited in 24 publications. Immunogen corresponding to Cell preparation containing CD31 protein.
IgG1
Mouse
FITC
Ex: 495nm, Em: 519nm
pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: PBS
Liquid
Monoclonal
Flow Cyt | |
---|---|
Human | Not recommended |
Rat | Tested |
Species | Dilution info | Notes |
---|---|---|
Species Rat | Dilution info 10 µL for 106 Cells | Notes Use 10μl for labeling 106 cells in 100μl. ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info - | Notes Use 10μl for labeling 106 cells in 100μl. ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-660 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils. Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal. Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes. Modulates bradykinin receptor BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells. Induces susceptibility to atherosclerosis.
Platelet endothelial cell adhesion molecule, PECAM-1, Pecam, Pecam1
Mouse Monoclonal CD31 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Rat samples. Cited in 24 publications. Immunogen corresponding to Cell preparation containing CD31 protein.
Platelet endothelial cell adhesion molecule, PECAM-1, Pecam, Pecam1
IgG1
Mouse
FITC
Ex: 495nm, Em: 519nm
pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: PBS
Liquid
Monoclonal
TLD-3A12
Affinity purification Protein G
Ab33858 recognises CD31 expressed primarily on endothelial cells, platelets and leucocytes.
Ab33858 was purified from tissue culture supernatant.
Blue Ice
+4°C
This clone (TLD 3A12) has been shown to partially block the proliferative response of antigen specific CD4+ T cells to antigen presenting cells and relevant antigen.
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
Figure A. RPE conjugated mouse anti rat TCRa/b and FITC conjugated mouse IgG1 isotype control. Figure B. RPE conjugated mouse anti rat TCRa/b and ab33858. All experiments performed on red cell lysed rat blood gated on mononuclear cells.
Figure A. ab33858 and RPE conjugated mouse IgG1 isotype control. Figure B. ab33858 and RPE conjugated mouse anti rat TCRa/b. All experiments performed on red cell lysed rat blood gated on mononuclear cells.
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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