AB21851

FITC Anti-CD41 antibody [MEM-06]

Name: FITC Anti-CD41 antibody [MEM-06] (ab21851) | Abcam
Brand: Abcam Limited
SKU: AB21851
Price: 95 USD
Availability: InStock

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(2 Publications)

Mouse Monoclonal CD41 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Cell preparation containing ITGA2B protein.

View Alternative Names

CD41, GP2B, ITGAB, ITGA2B, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb

1 Images

Flow Cytometry - FITC Anti-CD41 antibody [MEM-06] (AB21851)

Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-CD41 antibody [MEM-06] (AB21851)

Flow Cytometry analysis of human platelets labeling CD41 with ab21851.

Unconjugated

Anti-CD41 antibody [MEM-06]
667 PE/Cy5®

PE/Cy5® Anti-CD41 antibody [MEM-06]
578 PE

PE Anti-CD41 antibody [MEM-06]
Biotin

Biotin Anti-CD41 antibody [MEM-06]
660 APC

APC Anti-CD41 antibody [MEM-06]
778 PE/Cy7®

PE/Cy7® Anti-CD41 antibody [MEM-06]
723 Alexa Fluor® 700

Alexa Fluor® 700 Anti-CD41 antibody [MEM-06]
675 PerCP

PerCP Anti-CD41 antibody [MEM-06]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-06

Isotype

IgG1

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing ITGA2B protein. The exact immunogen used to generate this antibody is proprietary information.

P08514

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use 20μl of antibody per 100μl whole blood.</p><p><a href='/en-us/products/primary-antibodies/fitc-mouse-igg1-b11-6-isotype-control-ab91356'>ab91356</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

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Product details

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.4 Preservative: 0.097% Sodium azide Constituents: BSA, PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Integrin alpha-IIb/beta-3 (ITGA2B : ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (PubMed : 9111081). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity). Integrin ITGA2B : ITGB3 is also the receptor of erythrocyte-specific ICAM4 ligand involved in heterotypic cell-cell adhesion between erythrocytes and activated platelets (PubMed : 12477717).

See full target information ITGA2B

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 12:e2407574 PubMed39835574

2025

Extracellular Mitochondrial-Derived Vesicles Affect the Progression of Diabetic Foot Ulcer by Regulating Oxidative Stress and Mitochondrial Dysfunction.

Applications

Unspecified application

Species

Unspecified reactive species

Huihui Zhang,Zi Yan,Junyou Zhu,Ziyue Li,Lianglong Chen,Weihan Zheng,Zhenning Dai,Jiaxin Yang,Xinyi Yun,Yilin Wang,Hai Zhou,Ziwei Jiang,Qiuyi Yu,Shiyu Li,Wenhua Huang,Lei Yang

International journal of molecular sciences 25: PubMed39684778

2024

Exosomes Derived from Adipose Mesenhymal Stem Cells Ameliorate Lipid Metabolism Disturbances Following Liver Ischemia-Reperfusion Injury in Miniature Swine.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangyu Lu,Yue Wang,Chenxi Piao,Pujun Li,Lei Cao,Tao Liu,Yajun Ma,Hongbin Wang

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

FITC Anti-CD41 antibody [MEM-06]

Flow Cytometry - FITC Anti-CD41 antibody [MEM-06] (AB21851)

Related conjugates and formulations (8)

Key facts

Host species

Clonality

Clone number

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Publications (2)

Product promise