AB30401

FITC Anti-CD42b antibody [AK2]

Name: FITC Anti-CD42b antibody [AK2] (ab30401) | Abcam
Brand: Abcam Limited
SKU: AB30401
Price: 270 USD
Availability: InStock

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(2 Publications)

Mouse Monoclonal CD42b antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Cell preparation containing GP1BA protein.

View Alternative Names

CD42b, Platelet glycoprotein Ib alpha chain, GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha, GP1BA

1 Images

Flow Cytometry - FITC Anti-CD42b antibody [AK2] (AB30401)

Flow Cyt

Unknown

Flow Cytometry - FITC Anti-CD42b antibody [AK2] (AB30401)

FACS analysis of CD42b expressing cells in human peripheral blood platelets using ab30401.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

AK2

Isotype

IgG1

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing GP1BA protein. The exact immunogen used to generate this antibody is proprietary information.

P07359

Epitope

Epitope recognized by the antibody has been mapped to the first leucine rich repeat of CD42b (residues 36-59).

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use neat - 1/10. Use 10μl of the suggested working dilution to label 100μl whole blood.</p><p><a href='/en-us/products/primary-antibodies/fitc-mouse-igg1-b11-6-isotype-control-ab91356'>ab91356</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

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Product details

Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.

See full target information GP1BA

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Translational oncology 21:101433 PubMed35462210

2022

Eriodictyol mediated selective targeting of the TNFR1/FADD/TRADD axis in cancer cells induce apoptosis and inhibit tumor progression and metastasis.

Applications

Unspecified application

Species

Unspecified reactive species

Shibjyoti Debnath,Abhisek Sarkar,Dipanwita Das Mukherjee,Subha Ray,Barun Mahata,Tarun Mahata,Pravat K Parida,Troyee Das,Rupak Mukhopadhyay,Zhumur Ghosh,Kaushik Biswas

Biophysical journal 85:4099-109 PubMed14645097

2003

Kinetics of GPIbalpha-vWF-A1 tether bond under flow: effect of GPIbalpha mutations on the association and dissociation rates.

Applications

Unspecified application

Species

Unspecified reactive species

R Anand Kumar,Jing-fei Dong,Jenny A Thaggard,Miguel A Cruz,José A López,Larry V McIntire

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

FITC Anti-CD42b antibody [AK2]

Flow Cytometry - FITC Anti-CD42b antibody [AK2] (AB30401)

Key facts

Host species

Clonality

Clone number

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

Epitope

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Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Publications (2)

Product promise