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AB30405

FITC Anti-CD44 antibody [F10-44-2]

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(8 Publications)

Mouse Monoclonal CD44 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human, Cynomolgus monkey samples. Cited in 8 publications. Immunogen corresponding to Cell preparation containing CD44 protein.

View Alternative Names

CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I

1 Images
Flow Cytometry - FITC Anti-CD44 antibody [F10-44-2] (AB30405)
  • Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-CD44 antibody [F10-44-2] (AB30405)

FACS analysis of CD44 expressing cells in human peripheral blood lymphocytes using ab30405.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

F10-44-2

Isotype

IgG2a

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Human, Cynomolgus monkey

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing CD44 protein. The exact immunogen used to generate this antibody is proprietary information.

P16070

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/1 - 1/10", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/fitc-mouse-igg2a-x5563-isotype-control-ab91362'>ab91362</a> - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.</p>" }, "Cynomolgus monkey": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/1 - 1/10", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/fitc-mouse-igg2a-x5563-isotype-control-ab91362'>ab91362</a> - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.</p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

The protein expressed by gene CD44 functions as a cell-surface receptor involved in cell-cell interactions, cell adhesion, and migration, allowing cells to detect and react to changes in their tissue microenvironment. It is implicated in numerous cellular processes, including the activation, recirculation, and homing of T-lymphocytes, hematopoiesis, inflammation, and the response to bacterial infection. Through its ectodomain, CD44 interacts with extracellular matrix components like hyaluronan, collagen, growth factors, cytokines, and proteases, serving as a platform for signal transduction by forming protein complexes with receptor kinases and membrane proteases via its cytoplasmic domain. Effectors such as PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases, and phospholipase C coordinate signaling pathways that promote calcium mobilization and actin-mediated cytoskeleton reorganization crucial for cell migration and adhesion. This supplementary information is collated from multiple sources and compiled automatically.
See full target information CD44

Publications (8)

Recent publications for all applications. Explore the full list and refine your search

Journal of bone oncology 50:100655 PubMed39850453

2025

Using β-Elemene to reduce stemness and drug resistance in osteosarcoma: A focus on the AKT/FOXO1 signaling pathway and immune modulation.

Applications

Unspecified application

Species

Unspecified reactive species

Shaochun Zhang,Zhijie Xing,Jing Ke

PeerJ 11:e16523 PubMed38505381

2024

Circular RNA hsa_circ_0051246 acts as a microRNA-375 sponge to promote the progression of gastric cancer stem cells YAP1.

Applications

Unspecified application

Species

Unspecified reactive species

Minghui Deng,Yefeng Xu,Yongwei Yao,Yiqing Wang,Qingying Yan,Miao Cheng,YunXia Liu

Journal of nanobiotechnology 21:459 PubMed38037135

2023

Biomimetic composite hydrogel promotes new bone formation in rat bone defects through regulation of miR-19b-3p/WWP1 axis by loaded extracellular vesicles.

Applications

Unspecified application

Species

Unspecified reactive species

Rongkang Guo,Chaohan Wu,Fan Liu,Tianhua Dong,Tao Zhang

Nature microbiology 8:1051-1063 PubMed37188812

2023

Pan-sarbecovirus prophylaxis with human anti-ACE2 monoclonal antibodies.

Applications

Unspecified application

Species

Unspecified reactive species

Fengwen Zhang,Jesse Jenkins,Renan V H de Carvalho,Sandra Nakandakari-Higa,Teresia Chen,Morgan E Abernathy,Viren A Baharani,Elisabeth K Nyakatura,David Andrew,Irina V Lebedeva,Ivo C Lorenz,H-Heinrich Hoffmann,Charles M Rice,Gabriel D Victora,Christopher O Barnes,Theodora Hatziioannou,Paul D Bieniasz

Bioengineered 13:10827-10842 PubMed35470736

2022

Colorectal cancer stem cell-derived exosomal long intergenic noncoding RNA 01315 (LINC01315) promotes proliferation, migration, and stemness of colorectal cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Youran Li,Minna Wu,Shanshan Xu,Hua Huang,Lei Yan,Yunfei Gu

Frontiers in oncology 11:711735 PubMed34646768

2021

OTUB2 Facilitates Tumorigenesis of Gastric Cancer Through Promoting KDM1A-Mediated Stem Cell-Like Properties.

Applications

Unspecified application

Species

Unspecified reactive species

Guangming Liu,Wei Guo,Junjie Qin,Zhiliang Lin

International journal of molecular medicine 47:677-687 PubMed33416139

2021

Ultrasound‑targeted microbubble destruction‑mediated Galectin‑7‑siRNA promotes the homing of bone marrow mesenchymal stem cells to alleviate acute myocardial infarction in rats.

Applications

Unspecified application

Species

Unspecified reactive species

Xin Wei,Yan Zheng,Weilin Zhang,Jing Tan,Hong Zheng

International journal of cancer 80:387-95 PubMed9935179

1999

Involvement of CD44 in matrix metalloproteinase-2 regulation in human melanoma cells.

Applications

Unspecified application

Species

Unspecified reactive species

K Takahashi,H Eto,K K Tanabe
View all publications

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