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AB218749

FITC Anti-CD44 antibody [IM7]

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(1 Publication)

Rat Monoclonal CD44 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 1 publication.

View Alternative Names

CD44, Ly-24, Cd44, CD44 antigen, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Lymphocyte antigen 24, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I

1 Images
Flow Cytometry - FITC Anti-CD44 antibody [IM7] (AB218749)
  • Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-CD44 antibody [IM7] (AB218749)

Flow cytometic analysis of mouse C57BI/6 splenocytes labeling CD44 with 0.5 μg ab218749 (solid line) or 0.5 μg rat IgG2b FITC isotype control (dashed line).

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

IM7

Isotype

IgG2b

Light chain type

kappa

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Mouse

Applications

Flow Cyt

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "" }, "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use 0.5 μg.</p>" } } }
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Product details

ab218749 may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain.
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Purification notes
ab218749 was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Storage buffer
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases (PubMed : 25065622, PubMed : 8343954). Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion (By similarity).
See full target information Cd44
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Stem cells and development 23:1134-48 PubMed24368059

2014

Equine epidermis: a source of epithelial-like stem/progenitor cells with in vitro and in vivo regenerative capacities.

Applications

Unspecified application

Species

Unspecified reactive species

Sarah Y Broeckx,Sofie Maes,Tiziana Martinello,Désirée Aerts,Koen Chiers,Tom Mariën,Marco Patruno,Alfredo Franco-Obregón,Jan H Spaas
View all publications
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Product promise

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