Rat Monoclonal CD44 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 1 publication.
Images
![Flow Cytometry - FITC Anti-CD44 antibody [IM7] (AB218749), expandable thumbnail](https://content.abcam.com/products/images/fitc-cd44-antibody-im7-ab218749--flow-cytometry-img55784.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - FITC Anti-CD44 antibody [IM7] (AB218749)")
Publications
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- Stem cells and development 23:1134-482014Equine epidermis: a source of epithelial-like stem/progenitor cells with in vitro and in vivo regenerative capacities.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSarah Y Broeckx,Sofie Maes,Tiziana Martinello,Désirée Aerts,Koen Chiers,Tom Mariën,Marco Patruno,Alfredo Franco-Obregón,Jan H SpaasPubMed 24368059
Key facts
- Isotype
- IgG2b
- Host species
- Rat
- Conjugation
- FITC
- Excitation/Emission
- Ex: 495nm, Em: 519nm
- Storage buffer
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin- Form
- Liquid
- Clonality
- Monoclonal
Reactivity data
Select an application| Flow Cyt | |
|---|---|
| Human | Predicted |
| Mouse | Tested |
Flow Cyt
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes Use 0.5 μg. |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
Associated Products
Select an associated product type
5 products for Alternative Version
4 products for Alternative Product
Target data
Function
Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases (PubMed:25065622, PubMed:8343954). Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion (By similarity).
Alternative names
CD44, Ly-24, Cd44, CD44 antigen, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Lymphocyte antigen 24, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I
Recommended products
Rat Monoclonal CD44 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 1 publication.
Key facts
- Isotype
- IgG2b
- Host species
- Rat
- Conjugation
- FITC
- Excitation/Emission
- Ex: 495nm, Em: 519nm
- Storage buffer
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin- Form
- Liquid
- Clonality
- Monoclonal
- Clone number
- IM7
- Purification technique
- Affinity purification Protein A
- Light chain type
- kappa
- Concentration
- Purification notes
ab218749 was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
- Storage information
- Store in the dark
Notes
ab218749 may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain.
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Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
![Flow Cytometry - FITC Anti-CD44 antibody [IM7] (ab218749), expandable thumbnail](https://content.abcam.com/products/images/fitc-cd44-antibody-im7-ab218749--flow-cytometry-img55784.jpg "Flow Cytometry - FITC Anti-CD44 antibody [IM7] (ab218749)")
Flow Cytometry - FITC Anti-CD44 antibody [IM7] (ab218749)
Flow cytometic analysis of mouse C57BI/6 splenocytes labeling CD44 with 0.5 μg ab218749 (solid line) or 0.5 μg rat IgG2b FITC isotype control (dashed line).
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