Rat Monoclonal CD44 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 8 publications.
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![Flow Cytometry - FITC Anti-CD44 antibody [KM201] (AB25064), expandable thumbnail](https://content.abcam.com/products/images/fitc-cd44-antibody-km201-ab25064--flow-cytometry-img73254.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - FITC Anti-CD44 antibody [KM201] (AB25064)")
Publications
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- Research in pharmaceutical sciences 17:123-1332022Comparison of the efficacy of bone morphogenetic protein-4 on differentiation of murine adipose and bone marrow mesenchymal stem cells into primordial germ cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMaryam Hosseinzadeh Shirzeyli,Ali Tayyebiazar,Fereshteh Aliakbari,Fahimeh Ghasemi,Fatemeh Eini,Farhad Hosseinzadeh Shirzeyli,Elmira Vanaki,Aligholi SobhaniPubMed 35280837
- Molecular medicine reports 22:2767-27742020Role of the HIF‑1α/SDF‑1/CXCR4 signaling axis in accelerated fracture healing after craniocerebral injury.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYonghua Xue et. al.PubMed 32945380
- Frontiers in physiology 11:4412020Exosomal MicroRNA-320a Derived From Mesenchymal Stem Cells Regulates Rheumatoid Arthritis Fibroblast-Like Synoviocyte Activation by Suppressing CXCL9 Expression.Applications:Unspecified applicationReactive species:Unspecified reactive speciesQing Meng et. al.PubMed 32528301
- Journal of cellular physiology 234:23485-234942019Hypermethylation of microRNA-149 activates SDF-1/CXCR4 to promote osteogenic differentiation of mesenchymal stem cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGuangjie Li et. al.PubMed 31206187
- Microscopy research and technique 80:1151-11602017Bones Morphogenic Protein-4 and retinoic acid combined treatment comparative analysis for in vitro differentiation potential of murine mesenchymal stem cells derived from bone marrow and adipose tissue into germ cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMaryam H Shirzeyli,Neda Khanlarkhani,Fardin Amidi,Farshad H Shirzeyli,Fereydoon S Aval,Aligholi SobhaniPubMed 28921810
- Iranian journal of reproductive medicine 11:965-762014Comparison of differentiation potential of male mouse adipose tissue and bone marrow derived-mesenchymal stem cells into germ cells.Applications:Flow CytReactive species:MouseMaryam Hosseinzadeh Shirzeily,Parichehr Pasbakhsh,Fardin Amidi,Kobra Mehrannia,Aligholi SobhaniPubMed 24639722
- Biomaterials 33:7849-572012Synergistic effects of SDF-1α chemokine and hyaluronic acid release from degradable hydrogels on directing bone marrow derived cell homing to the myocardium.Applications:BLReactive species:Unspecified reactive speciesBrendan P Purcell et. al.PubMed 22835643
- Journal of immunology (Baltimore, Md. : 1950) 181:1937-472008Lack of plasma protein hemopexin dampens mercury-induced autoimmune response in mice.Applications:Flow CytReactive species:MouseSharmila Fagoonee,Cristiana Caorsi,Mirella Giovarelli,Meredin Stoltenberg,Lorenzo Silengo,Fiorella Altruda,Giovanni Camussi,Emanuela Tolosano,Benedetta BussolatiPubMed 18641331
Key facts
- Isotype
- IgG1
- Host species
- Rat
- Conjugation
- FITC
- Excitation/Emission
- Ex: 495nm, Em: 519nm
- Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
Reactivity data
Select an application| Flow Cyt | |
|---|---|
| Mouse | Tested |
Flow Cyt
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 2 µg for 106 Cells | Notes ab18404 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
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Target data
Function
Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment (PubMed:16541107, PubMed:19703720, PubMed:22726066). Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection (PubMed:7528188). Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases (PubMed:18757307, PubMed:23589287). Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion (PubMed:15123640).
Alternative names
CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I
Recommended products
Rat Monoclonal CD44 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 8 publications.
Key facts
- Isotype
- IgG1
- Host species
- Rat
- Conjugation
- FITC
- Excitation/Emission
- Ex: 495nm, Em: 519nm
- Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
- Clone number
- KM201
- Purification technique
- Affinity purification
- Specificity
Recognises all isoforms of CD44/pgp-1 (Mr 80-95 kDa)
- Epitope
- Reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule.
- Light chain type
- kappa
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
- Storage information
- Store in the dark
Notes
ab25064 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte Cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.
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1 product image
![Flow Cytometry - FITC Anti-CD44 antibody [KM201] (ab25064), expandable thumbnail](https://content.abcam.com/products/images/fitc-cd44-antibody-km201-ab25064--flow-cytometry-img73254.jpg "Flow Cytometry - FITC Anti-CD44 antibody [KM201] (ab25064)")
Flow Cytometry - FITC Anti-CD44 antibody [KM201] (ab25064)
ab25064 (at a concentration of 1 μg/106 cells) staining cells from BALB/c bone were stained by flow cytometry. Large cells were then gated and analyzed on a FACScan™ flow cytometer (BDIS, San Jose, CA).
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