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AB95138

FITC Anti-CD44 antibody [MEM-263]

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(4 Publications)

Mouse Monoclonal CD44 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human, Pig, Dog samples. Cited in 4 publications. Immunogen corresponding to Cell preparation containing CD44 protein.

View Alternative Names

CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I

2 Images
Flow Cytometry - FITC Anti-CD44 antibody [MEM-263] (AB95138)
  • Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-CD44 antibody [MEM-263] (AB95138)

Flow cytometry surface staining pattern of human peripheral whole blood stained using ab95138 (20 μl reagent / 100 μl of peripheral whole blood).

Flow Cytometry - FITC Anti-CD44 antibody [MEM-263] (AB95138)
  • Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-CD44 antibody [MEM-263] (AB95138)

Separation of human monocytes (red-filled) from CD44 negative blood debris (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using ab95138 (10 μl reagent / 100 μl of peripheral whole blood).

  • Unconjugated

    Anti-CD44 antibody [MEM-263]

  • 660 APC

    APC Anti-CD44 antibody [MEM-263]

  • 578 PE

    PE Anti-CD44 antibody [MEM-263]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-263

Isotype

IgG1

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Dog, Human, Pig

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing CD44 protein. The exact immunogen used to generate this antibody is proprietary information.

P16070

Specificity

ab95138 reacts with extracellular (N-terminal) domain of standard CD44 a 80-95 kDa transmembrane glycoprotein(hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.); it is negative on platelets and hepatocytes.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "20 µL for 10^6 Cells", "FlowCyt-species-notes": "<p>Use 20 μl reagent / 100 μl of whole blood or 10^6 cells in a suspension.<br><br><a href='/en-us/products/primary-antibodies/fitc-mouse-igg1-b11-6-isotype-control-ab91356'>ab91356</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" }, "Dog": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/fitc-mouse-igg1-b11-6-isotype-control-ab91356'>ab91356</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" }, "Pig": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/fitc-mouse-igg1-b11-6-isotype-control-ab91356'>ab91356</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Size-exclusion chromatography
Storage buffer
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS, 0.2% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

The protein expressed by gene CD44 functions as a cell-surface receptor involved in cell-cell interactions, cell adhesion, and migration, allowing cells to detect and react to changes in their tissue microenvironment. It is implicated in numerous cellular processes, including the activation, recirculation, and homing of T-lymphocytes, hematopoiesis, inflammation, and the response to bacterial infection. Through its ectodomain, CD44 interacts with extracellular matrix components like hyaluronan, collagen, growth factors, cytokines, and proteases, serving as a platform for signal transduction by forming protein complexes with receptor kinases and membrane proteases via its cytoplasmic domain. Effectors such as PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases, and phospholipase C coordinate signaling pathways that promote calcium mobilization and actin-mediated cytoskeleton reorganization crucial for cell migration and adhesion. This supplementary information is collated from multiple sources and compiled automatically.
See full target information CD44

Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Advanced healthcare materials 12:e2301180 PubMed37463568

2023

Selective Extracellular Matrix Guided Mesenchymal Stem Cell Self-Aggregate Engineering for Replication of Meniscal Zonal Tissue Gradient in a Porcine Meniscectomy Model.

Applications

Unspecified application

Species

Unspecified reactive species

Sujin Noh,Yong Jun Jin,Dong Il Shin,Hyeon Jae Kwon,Hee-Woong Yun,Kyu Min Kim,Jae-Young Park,Jun Young Chung,Do Young Park

Journal of oral biology and craniofacial research 13:403-411 PubMed37113531

2023

investigation of canine periodontal ligament-derived mesenchymal stem cells: A possibility of promising tool for periodontal regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Hamideh Salari Sedigh,Anna Saffarpour,Shahram Jamshidi,Mahdi Ashouri,Seyed Mahdi Nassiri,Mohammad Mehdi Dehghan,Esmail Ranjbar,Reyhaneh Shafieian

Heliyon 7:e07273 PubMed34235281

2021

Biological characteristics of a sub-population of cancer stem cells from two triple-negative breast tumour cell lines.

Applications

Unspecified application

Species

Unspecified reactive species

Javier Enciso-Benavides,Luis Alfaro,Carlos Castañeda-Altamirano,Nancy Rojas,José González-Cabeza,Nathaly Enciso,Fernando Riesco,Miluska Castillo,Javier Enciso

Biology open 9: PubMed32086253

2020

Nanomorphological and mechanical reconstruction of mesenchymal stem cells during early apoptosis detected by atomic force microscopy.

Applications

Unspecified application

Species

Unspecified reactive species

Xuelian Su,Haijing Zhou,Guangjie Bao,Jizeng Wang,Lin Liu,Qian Zheng,Manli Guo,Jinting Zhang
View all publications

Product promise

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