AB124527

FITC Anti-CD90 / Thy1 antibody [5E10]

Name: FITC Anti-CD90 / Thy1 antibody [5E10] (ab124527) | Abcam
Brand: Abcam Limited
SKU: AB124527
Price: 95 USD
Availability: InStock

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(30 Publications)

Mouse Monoclonal CD90 / Thy1 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human samples. Cited in 30 publications. Immunogen corresponding to Cell preparation containing THY1 protein.

View Alternative Names

CD90, Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, THY1

1 Images

Flow Cytometry - FITC Anti-CD90 / Thy1 antibody [5E10] (AB124527)

Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-CD90 / Thy1 antibody [5E10] (AB124527)

Flow cytometry analysis (surface staining) using ab124527 (4 µL reagent per milion cells in 100 µL of cell suspension). Histogram showing separation of Jurkat cells (red) from SP2 cells (black).

Unconjugated

Anti-CD90 / Thy1 antibody [5E10]
660 APC

APC Anti-CD90 / Thy1 antibody [5E10]
695 PerCP/Cy5.5®

PerCP/Cy5.5® Anti-CD90 / Thy1 antibody [5E10]
667 PE/Cy5®

PE/Cy5® Anti-CD90 / Thy1 antibody [5E10]
578 PE

PE Anti-CD90 / Thy1 antibody [5E10]
785 APC/Cy7®

APC/Cy7® Anti-CD90 / Thy1 antibody [5E10]
Biotin

Biotin Anti-CD90 / Thy1 antibody [5E10]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

5E10

Isotype

IgG1

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing THY1 protein. The exact immunogen used to generate this antibody is proprietary information.

P04216

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>4 μl reagent / 100 μl of whole blood or 10<sup>6</sup> cells in a suspension.</p>" } } }

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Product details

The reagent is free of unconjugated FITC and adjusted for direct use.

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Properties and storage information

Form

Liquid

Purification technique

Size-exclusion chromatography

Storage buffer

pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS, 0.2% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).

Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

See full target information THY1

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Publications (30)

Recent publications for all applications. Explore the full list and refine your search

Stem cells translational medicine 14: PubMed40371959

2025

Immune rejection of human mesenchymal stem cells compared to extracellular vesicles in mice with renal artery stenosis.

Applications

Unspecified application

Species

Unspecified reactive species

Tarek Ziad Arabi,Yazan Almasry,Ailing Xue,Alfonso Eirin,Amir Lerman,Xiang-Yang Zhu,Lilach O Lerman

International journal of molecular sciences 25: PubMed39684778

2024

Exosomes Derived from Adipose Mesenhymal Stem Cells Ameliorate Lipid Metabolism Disturbances Following Liver Ischemia-Reperfusion Injury in Miniature Swine.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangyu Lu,Yue Wang,Chenxi Piao,Pujun Li,Lei Cao,Tao Liu,Yajun Ma,Hongbin Wang

Stem cell research & therapy 15:162 PubMed38853239

2024

The impact of hypoxia preconditioning on mesenchymal stem cells performance in hypertensive kidney disease.

Applications

Unspecified application

Species

Unspecified reactive species

Gurparneet Kaur Sohi,Naba Farooqui,Arjunmohan Mohan,Kamalnath Sankaran Rajagopalan,Li Xing,Xiang Y Zhu,Kyra Jordan,James D Krier,Ishran M Saadiq,Hui Tang,LaTonya J Hickson,Alfonso Eirin,Lilach O Lerman,Sandra M Herrmann

Scientific reports 14:6777 PubMed38514682

2024

Human dental pulp stem cells derived extracellular matrix promotes mineralization via Hippo and Wnt pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Chatvadee Kornsuthisopon,Nunthawan Nowwarote,Ajjima Chansaenroj,Suphalak Photichailert,Sunisa Rochanavibhata,Nuttha Klincumhom,Stephane Petit,Florent Dingli,Damarys Loew,Benjamin P J Fournier,Thanaphum Osathanon

Dental materials journal 43:20-27 PubMed38008439

2023

Induction of mesenchymal stem cell (MSC) differentiation from iPS cells using MSC medium.

Applications

Unspecified application

Species

Unspecified reactive species

Yufan Wu,Kengo Iwasaki,Yoshiya Hashimoto

International endodontic journal 57:219-236 PubMed37971040

2023

IWP-2 modulates the immunomodulatory properties of human dental pulp stem cells in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Ajjima Chansaenroj,Chatvadee Kornsuthisopon,Ravipha Suwittayarak,Sunisa Rochanavibhata,Lai-Keng Loi,Yu-Cheng Lin,Thanaphum Osathanon

Stem cell research & therapy 14:49 PubMed36949528

2023

Diabetic kidney disease induces transcriptome alterations associated with angiogenesis activity in human mesenchymal stromal cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaohui Bian,Sabena M Conley,Alfonso Eirin,Eric A Zimmerman Zuckerman,Anastasia L Smith,Cody C Gowan,Zachary K Snow,Tambi Jarmi,Houssam Farres,Young M Erben,Albert G Hakaim,Matthew A Dietz,Abba C Zubair,Saranya P Wyles,Joy V Wolfram,Lilach O Lerman,LaTonya J Hickson

Proceedings of the National Academy of Sciences of the United States of America 120:e2214757120 PubMed36574680

2022

Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions.

Applications

Unspecified application

Species

Unspecified reactive species

Da Zou,Zeming Wu,Xin Yi,Yue Hui,Guangze Yang,Yun Liu, Tengjisi,Haofei Wang,Anastasia Brooks,Haolu Wang,Xin Liu,Zhi Ping Xu,Michael S Roberts,Huajian Gao,Chun-Xia Zhao

International endodontic journal 56:369-384 PubMed36458950

2022

Tideglusib enhances odontogenic differentiation in human dental pulp stem cells in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Chatvadee Kornsuthisopon,Kevin A Tompkins,Thanaphum Osathanon

BDJ open 8:31 PubMed36207319

2022

Betaine promotes osteogenic differentiation in immortalized human dental pulp-derived cells.

Applications

Unspecified application

Species

Unspecified reactive species

Chatvadee Kornsuthisopon,Dusit Nantanapiboon,Sunisa Rochanavibhata,Nunthawan Nowwarote,Worachat Namangkalakul,Thanaphum Osathanon

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

FITC Anti-CD90 / Thy1 antibody [5E10]

Flow Cytometry - FITC Anti-CD90 / Thy1 antibody [5E10] (AB124527)

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Key facts

Host species

Clonality

Clone number

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (30)

Product promise