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Rabbit Recombinant Monoclonal Coxsackie Adenovirus Receptor/hCAR antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human CXADR aa 1-250.

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Images

Flow Cytometry - FITC Anti-Coxsackie Adenovirus Receptor/hCAR antibody [271] (AB275683), expandable thumbnail

Key facts

Isotype
IgG
Host species
Rabbit
Conjugation
FITC
Excitation/Emission
Ex: 495nm, Em: 519nm
Storage buffer

Preservative: 0.09% Sodium azide
Constituents: 0.5% BSA

Form
Liquid
Clonality
Monoclonal

Immunogen

  • Recombinant Fragment Protein within Human CXADR aa 1-250. The exact immunogen used to generate this antibody is proprietary information. Database link P78310

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
Flow Cyt
Human
Tested

Tested
Tested

Species
Human
Dilution info
-
Notes

10 μL/Test

Target data

Function

Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. (Microbial infection) Acts as a receptor for adenovirus type C. (Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6.

Alternative names

CAR, CXADR, Coxsackievirus and adenovirus receptor, hCAR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR

Recommended products

Rabbit Recombinant Monoclonal Coxsackie Adenovirus Receptor/hCAR antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human CXADR aa 1-250.

Key facts

Isotype
IgG
Conjugation
FITC
Excitation/Emission
Ex: 495nm, Em: 519nm
Form
Liquid
Clonality
Monoclonal
Immunogen
  • Recombinant Fragment Protein within Human CXADR aa 1-250. The exact immunogen used to generate this antibody is proprietary information. Database link P78310
Clone number
271
Purification technique
Affinity purification Protein A
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze, Store in the dark

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Flow Cytometry - FITC Anti-Coxsackie Adenovirus Receptor/hCAR antibody [271] (ab275683), expandable thumbnail

    Flow Cytometry - FITC Anti-Coxsackie Adenovirus Receptor/hCAR antibody [271] (ab275683)

    Flow cytometric analysis of Coxsackie Adenovirus Receptor/hCAR expression on HT-29 (Human colorectal adenocarcinoma cell line) cells. HT-29 cells were stained with ab275683 at 10 μl/Test. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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