JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB74085

FITC Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37]

Be the first to review this product! Submit a review

|

(2 Publications)

Mouse Monoclonal GB antibody - conjugated to FITC. Suitable for ICC/IF and reacts with Human cytomegalovirus samples. Cited in 2 publications.

View Alternative Names

UL55, gB, Envelope glycoprotein B

  • Unconjugated

    Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

HCMV37

Isotype

IgG2a

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Human cytomegalovirus

Applications

ICC/IF

applications

Specificity

ab74085 reacts with MRC-5 infected cells but not uninfected cells. This antibody has been found to be neutralizing.

style
left-column

Alternative Products

Primary Antibodies

AB6499

Anti-Cytomegalovirus Glycoprotein B antibody [2F12]

Immunocytochemistry/ Immunofluorescence - Anti-Cytomegalovirus Glycoprotein B antibody [2F12] (AB6499)

  • 5
  • 1

Complementary Products

Proteins & Peptides

AB43040

Recombinant Cytomegalovirus Glycoprotein B

  • 0
  • 0
Primary Antibodies

AB53495

Anti-Cytomegalovirus IE1 and IE2 antibody [CH160] - BSA and Azide free

  • 0
  • 0
Primary Antibodies

AB6502

Anti-Cytomegalovirus pp28 antibody [5C3]

ELISA - Anti-Cytomegalovirus pp28 antibody [5C3] (AB6502)

  • 0
  • 0
Proteins & Peptides

AB43046

Recombinant HSV2 gD protein

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human cytomegalovirus": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
See full target information gB
style
left-column

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Brain : a journal of neurology 147:2334-2343 PubMed38527963

2024

RTN2 deficiency results in an autosomal recessive distal motor neuropathy with lower limb spasticity.

Applications

Unspecified application

Species

Unspecified reactive species

Reza Maroofian,Payam Sarraf,Thomas J O'Brien,Mona Kamel,Arman Cakar,Nour Elkhateeb,Tracy Lau,Siddaramappa Jagdish Patil,Christopher J Record,Alejandro Horga,Miriam Essid,Laila Selim,Hanene Benrhouma,Thouraya Ben Younes,Giovanni Zifarelli,Alistair T Pagnamenta,Peter Bauer,Mukhran Khundadze,Andrea Mirecki,Sara Mahmoud Kamel,Mohamed A Elmonem,Ehsan Ghayoor Karimiani,Yalda Jamshidi,Amaka C Offiah,Alexander M Rossor,Ilhem Ben Youssef-Turki,Christian A Hübner,Pinki Munot,Mary M Reilly,André E X Brown,Sara Nagy,Henry Houlden

The EMBO journal 5:3057-63 PubMed3024973

1986

Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus.

Applications

Unspecified application

Species

Unspecified reactive species

M P Cranage,T Kouzarides,A T Bankier,S Satchwell,K Weston,P Tomlinson,B Barrell,H Hart,S E Bell,A C Minson
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com