AB4217

FITC Anti-Fibrinogen antibody

Name: FITC Anti-Fibrinogen antibody (ab4217) | Abcam
Brand: Abcam Limited
SKU: AB4217
Price: 540 USD
Availability: InStock
Rating: 4 (1 reviews)

(1 Review)

(2 Publications)

Rabbit Polyclonal Fibrinogen alpha chain antibody - conjugated to FITC. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human FGA.

View Alternative Names

Fibrinogen alpha chain, FGA

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FITC Anti-Fibrinogen antibody (AB4217)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FITC Anti-Fibrinogen antibody (AB4217)

Immunohistochemical analysis of Formalin-fixed paraffin-embedded human placenta labeling Fibrinogen with ab4217 (left -low magnification; and right - high magnification).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

Reacts with

Human

Applications

ICC/IF, IHC-P

applications

Immunogen

Native Full Length Protein corresponding to Human FGA.

P02671

Specificity

This antibody reacts with native fibrinogen as well as with the fibrinogen fragments D, E, X and Y.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purity

IgG fraction

Purification notes

Traces of contaminating antibodies have been removed by solid phase absorption with human plasma proteins.

Storage buffer

pH: 7.3 - 7.5 Preservative: 0.05% Sodium azide Constituents: 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

See full target information FGA

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Journal of dental sciences 18:1008-1015 PubMed37404619

2023

Clinical, histological and direct immunofluorescence features in oral mucosal patches striae diseases with malignant potential.

Applications

Unspecified application

Species

Unspecified reactive species

Chun-Lei Li,Xiao-Meng Ren,Xin Fang,Hai-Yan Luo,Hong Hua

Journal of the Royal Society, Interface 11:20131079 PubMed24554575

2014

Macro- and microscale variables regulate stent haemodynamics, fibrin deposition and thrombomodulin expression.

Applications

Unspecified application

Species

Unspecified reactive species

Juan M Jiménez,Varesh Prasad,Michael D Yu,Christopher P Kampmeyer,Abdul-Hadi Kaakour,Pei-Jiang Wang,Sean F Maloney,Nathan Wright,Ian Johnston,Yi-Zhou Jiang,Peter F Davies

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

FITC Anti-Fibrinogen antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FITC Anti-Fibrinogen antibody (AB4217)

Key facts

Host species

Clonality

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

Specificity

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Reactivity data

Properties and storage information

Form

Purity

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Publications (2)

Product promise