Goat Polyclonal HSV1 antibody - conjugated to FITC. Suitable for ELISA, ICC/IF and reacts with Herpes simplex virus samples. Cited in 1 publication. Immunogen corresponding to Virus preparation containing HSV1 protein.
Preservative: 0.1% Sodium azide
Constituents: 1% BSA, 0.0268% PBS
| ELISA | ICC/IF | |
|---|---|---|
| Herpes simplex virus | Expected | Expected |
| Species | Dilution info | Notes |
|---|---|---|
Species Herpes simplex virus | Dilution info 1/10 - 1/50 | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Herpes simplex virus | Dilution info Use at an assay dependent concentration. | Notes - |
Select an associated product type
Herpes simplex virus, Herpes simplex virus 1, Herpes simplex virus type 1, Human Herpesvirus 1, Human herpesvirus type 1
Goat Polyclonal HSV1 antibody - conjugated to FITC. Suitable for ELISA, ICC/IF and reacts with Herpes simplex virus samples. Cited in 1 publication. Immunogen corresponding to Virus preparation containing HSV1 protein.
Preservative: 0.1% Sodium azide
Constituents: 1% BSA, 0.0268% PBS
ICPs and late structural (virion) antigens.
IgG fraction covalently coupled with high purity Isomer I of fluorescein isothiocyanate. Care is taken to ensure complete removal of any free fluorescein from the final product.
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Herpes Simplex Virus 1 (HSV1) also referred to as HSV-1 is an enveloped virus with a large double-stranded DNA genome of about 152 kb. HSV1 possesses a complex architecture featuring numerous glycoproteins including gHSV1 that play significant roles in its entry and immune evasion. This virus predominantly targets epithelial cells in the oral genital regions and sensory neurons. HSV1 expresses various proteins vital for its replication and viral particle assembly within host cells.
HSV1 interacts with the host's cellular mechanisms to establish latency and persistent infection. During infection several HSV1 proteins contribute to its ability to subvert and evade the host immune response sometimes forming part of existing viral protein complexes. Virion-host cell membrane fusion facilitated by glycoprotein gHSV1 is an important step allowing the viral genome to enter the host cell driving subsequent viral replication.
The life cycle of HSV1 includes entry replication and egress tightly integrated into cellular pathways like the apoptosis and the interferon response pathways. HSV1 modulates the apoptotic pathway through proteins such as ICP22 which allows survival and efficient viral replication. Also it influences the interferon response pathway by inhibiting the host's antiviral mechanisms ensuring viral persistence in the host.
HSV1 is most commonly known to cause oral herpes and can lead to encephalitis in severe cases. The virus reactivates from latency within neurons potentially leading to periodic disease recurrence. During infection HSV1 interacts with host proteins such as TNF-alpha which can contribute to inflammatory responses and ICP0 which facilitates viral replication and disrupts host cell function. Understanding HSV1's mechanisms and pathways is critical for developing effective anti-HSV-1 antibodies and therapeutic strategies.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com